MYB anticorps (AA 119-135)

N° du produit ABIN3026199

L’anticorps Souris Monoclonal anti-MYB a été validé pour IF et FACS. Il convient pour détecter MYB dans des échantillons de Humain.

Aperçu rapide pour MYB anticorps (AA 119-135) (ABIN3026199)

Antigène: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp MYB est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: MYB286

Détail du produit anti-MYB anticorps

Épitope: AA 119-135

Purification: Protein G affinity chromatography

Immunogène: Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.

Isotype: IgG1 kappa

Information d'application

Indications d'application: The optimal dilution of the c-Myb antibody for each application should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence (1-2 μg/mL)

Restrictions: For Research Use only

Stockage

Concentration: 0.2 mg/mL

Buffer: 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Store the c-Myb antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur MYB

Antigène: MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))

Autre désignation: C-Myb

Sujet: The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.

Pathways: Chromatin Binding, Positive Regulation of Immune Effector Process