MYB anticorps (AA 119-135)
Aperçu rapide pour MYB anticorps (AA 119-135) (ABIN3026200)
Antigène
Voir toutes MYB AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Épitope
- AA 119-135
-
Purification
- Protein G affinity chromatography
-
Immunogène
- Amino acids 119-135 (RRKVEQEGYPQESSKAG) from the human protein were used as the immunogen for this c-Myb antibody.
-
Isotype
- IgG1 kappa
-
-
-
-
Indications d'application
- The optimal dilution of the c-Myb antibody for each application should be determined by the researcher.\. Flow Cytometry: 0.5-1 μg/million cells in 0.1ml,Immunofluorescence (1-2 μg/mL)
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 1 mg/mL
-
Buffer
- 1 mg/mL in 1X PBS, BSA free, sodium azide free
-
Agent conservateur
- Azide free
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store the c-Myb antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
-
- MYB (V-Myb Myeloblastosis Viral Oncogene Homolog (Avian) (MYB))
-
Autre désignation
- C-Myb
-
Sujet
- The highly leukemogenic avian retrovirus E26 contains two oncogenes, v-Myb and v-Ets, which are expressed together as a fusion protein. The cellular homolog of v-Myb, designated c-Myb, encodes a transcription factor. Deletion or disruption of a negative regulatory domain mapping within the carboxy-terminal domain of c-Myb results in enhanced transactivating capacity and in parallel, leads to activation of its ability to transform hemopoietic cells. c-Myb is expressed preferentially, but not exclusively, in immature hemopoietic cells and its expression decreases as cells differentiate.
-
Pathways
- Chromatin Binding, Positive Regulation of Immune Effector Process
Antigène
-