HSPD1 anticorps
Aperçu rapide pour HSPD1 anticorps (ABIN3026478)
Antigène
Voir toutes HSPD1 AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
Clone
-
-
Attributs du produit
- This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.
-
Purification
- Protein G affinity chromatography
-
Immunogène
- Recombinant human HSP60 protein was used as the immunogen for this antibody.
-
Isotype
- IgG1 kappa
-
-
-
-
Indications d'application
- The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. FACS: 0.5-1 μg/million cells,IF: 1-2 μg/mL,WB: 1-2 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Concentration
- 0.2 mg/mL
-
Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
-
Agent conservateur
- Sodium azide
-
Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
-
Stock
- 4 °C,-20 °C
-
Stockage commentaire
- Store the HSP60 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
-
-
- HSPD1 (Heat Shock 60kDa Protein 1 (Chaperonin) (HSPD1))
-
Autre désignation
- HSP60
-
Sujet
- This antibody recognizes a 60 kDa protein, identified as the heat shock protein 60 (hsp60). The antibody's epitope is localized between amino acids 383-419 of human HSP60. A wide variety of environmental and pathophysiological stressful conditions trigger the synthesis of a family of proteins known as heat shock proteins (hsp's), more appropriately called as stress response proteins (srp's). HSP60 is a potential antigen in a number of autoimmune diseases. In human arthritis and in experimentally induced arthritis in animals, disease development coincides with the development of immune reactivity directed against not only bacterial HSP60, but also against its mammalian homolog. Clone LK2 antibody, unlike LK1 antibody, recognizes both mammalian and bacterial HSP60.
-
ID gène
- 3329
-
Pathways
- Activation of Innate immune Response, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity
Antigène
-