Ku70 + Ku80 anticorps

N° du produit ABIN3026515

Cet anticorps anti-Ku70 + Ku80 Monoclonal Souris (Clone KU729) (ABIN3026515) détecte spécifiquement Ku70 + Ku80 dans IF, FACS et ICC. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Ku70 + Ku80 anticorps (ABIN3026515)

Antigène: Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ku70 + Ku80 est non-conjugé

Application: Immunofluorescence (IF), Flow Cytometry (FACS), Immunocytochemistry (ICC)

Classe de qualité: Carrier-free

Clone: KU729

Détail du produit anti-Ku70 + Ku80 anticorps

Fonction: Ku70 + Ku80 Antibody (azide and preservative free)

Aucune reactivité croisée: Souris, Rat (Rattus), Poulet

Attributs du produit: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.

Purification: Protein G purified monoclonal antibody

Immunogène: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the Ku70 + Ku80 antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the Ku70 + Ku80 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur Ku70 + Ku80

Antigène: Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

Autre désignation: Ku70 + Ku80

Sujet: This antibody recognizes a dimer of two proteins of 70 kDa (Ku70) and ~80 kDa (Ku80), identified as two subunits of Ku. Antbody KU729 recognizes a conformational epitope of the Ku70 + Ku80 dimer, which is destroyed during Western blotting. The Ku70 + Ku80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.