Ku70 + Ku80 anticorps (CF®488A)

N° du produit ABIN7880388

L’anticorps anti-Ku70 + Ku80 Monoclonal Souris est utilisé pour la détection de Ku70 + Ku80 dans des échantillons de Humain. Il a été validé pour IF et FACS.

Aperçu rapide pour Ku70 + Ku80 anticorps (CF®488A) (ABIN7880388)

Antigène: Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Ku70 + Ku80 est conjugé à/à la CF®488A

Application: Immunofluorescence (IF), Flow Cytometry (FACS)

Clone: KU729

Détail du produit anti-Ku70 + Ku80 anticorps (CF®488A)

Fonction: Ku70 + Ku80 Antibody

Purification: Protein G affinity chromatography

Immunogène: Nuclear extract of human HL-60 cells was used as the immunogen for this Ku70 + Ku80 antibody.

Isotype: IgG1, kappa

Information d'application

Indications d'application: Optimal dilution of the Ku70 + Ku80 antibody should be determined by the researcher.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: 500 µL at 0.1 mg/mL with 0.1 mg/mL BSA (US sourced), 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C

Stockage commentaire: Store the Ku70 + Ku80 antibody at 2-8oC, protected from light.

Détails sur Ku70 + Ku80

Antigène: Ku70 + Ku80 (KU80) (CG18801 Gene Product From Transcript CG18801-RA (KU80))

Autre désignation: Ku70 + Ku80

Sujet: Recognizes a dimer of two proteins of 70 kDa and ~80 kDa, identified as two subunits of Ku. MAb KU729 recognizes a conformational epitope of p70/p80 dimer, which is destroyed during Western blotting. The p70/p80 dimer is important for function of a 460 kDa DNA-dependent protein kinase. Ku protein plays a role in cell signaling, proliferation, DNA repair, replication, transcriptional activation, and apoptosis.