IL-24 anticorps (AA 100-150)

N° du produit ABIN302672

Détail du produit anti-IL-24 anticorps

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Épitope: AA 100-150

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-24 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Flow Cytometry (FACS)

Specificité: This antibody recognizes Interleukin 24 (IL24/Mda-7).

Réactivité croisée (Details): Species reactivity (tested):Human.

Purification: Protein G Chromatography

Immunogène: A portion of amino acids 100-150 of human IL-24 was used as the immunogen.

Isotype: IgG

Information d'application

Indications d'application: Flow Cytometry. Western Blot: 0.5-3 μg/mL. Immunohistochemistry on Paraffin Sections: 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: PBS, 0.05 % Sodium Azide, 0.2 % Gelatin

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer.

Détails sur IL-24

Antigène: IL-24 (IL24) (Interleukin 24 (IL24))

Autre désignation: Interleukin-24 / IL24 (IL24 Produits)

Synonymes: anticorps C49A, anticorps FISP, anticorps IL10B, anticorps MDA7, anticorps MOB5, anticorps ST16, anticorps Mda7, anticorps St16, anticorps Mda-7, anticorps IL24, anticorps interleukin 24, anticorps IL24, anticorps Il24

Sujet: Interleukin 24 (IL-24)/melanoma differentiation-associated gene-7 (mda-7) encodes a secreted protein that exhibits significant homology to the interleukin 10 (IL-10) family of cytokines. The human IL-24 is secreted by activated peripheral blood mononuclear cells and binds two heterodimeric receptors, IL-22R1/IL-20R2 and IL-20R1/IL-20R2 resulting in the activation of JAK/STAT signaling pathways. Mda-7/IL-24, selectively induces growth suppression, apoptosis and radiosensitization in malignant gliomas in a p53-independent manner.Synonyms: IL-24, MDA7, Melanoma differentiation-associated gene 7 protein, ST16, Suppression of tumorigenicity 16 protein

ID gène: 11009

NCBI Accession: NP_001172085

UniProt: Q13007

Pathways: Cellular Response to Molecule of Bacterial Origin, Positive Regulation of Endopeptidase Activity, Autophagy