USP18 anticorps

N° du produit ABIN302692

Détail du produit anti-USP18 anticorps

Antigène: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp USP18 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Specificité: This antibody reacts to amino acids 40 to 49 of human USP18.

Purification: Immunoaffinity Chromatography

Immunogène: Synthetic peptide

Information d'application

Indications d'application: Immunofluorescence. Western Blot: 1: 500 - 1: 2000. Immunohistochemistry: 5 μg/mL. ELISA: 1: 10000 - 1: 50000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 0.93 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: -20 °C

Détails sur USP18

Antigène: USP18 (Ubiquitin Specific Peptidase 18 (USP18))

Autre désignation: USP18 (USP18 Produits)

Synonymes: anticorps ISG43, anticorps UBP43, anticorps bubp43, anticorps 1110058H21Rik, anticorps AW047653, anticorps Ubp15, anticorps UBP, anticorps USP18, anticorps USP41, anticorps ubiquitin specific peptidase 18, anticorps USP18, anticorps Usp18

Sujet: UBP43 (also known as ISG43, Ubl thiolesterase 18, ISG15-specific processing protease, 43 kDa ISG15-specific protease, ubiquitin specific protease 18 or USP18) is a member of the deubiquitinating protease family of enzymes, which removes ubiquitin adducts from a broad range of protein substrates. Deletion of the UBP43 gene in mouse leads to a massive increase of ISG15 conjugates in tissues indicating that UBP43 is a major ISG15-specific protease. UBP43 is the first ISG15-specific protease reported. Both ISG15 and UBP43 genes are known to be strongly induced by interferon, genotoxic stress, and viral infection. Thus UBP43 may be necessary to maintain a critical cellular balance of ISG15-conjugated proteins in both healthy and stressed organisms.Synonyms: 43 kDa ISG15-specific protease, ISG15-specific-processing protease, ISG43, Ubl carboxyl-terminal hydrolase 18, Ubl thioesterase 18

ID gène: 11274

NCBI Accession: NP_059110

UniProt: Q9UMW8