IL-21 anticorps (Center)

N° du produit ABIN302822

L’anticorps anti-IL-21 Polyclonal Lapin est utilisé pour la détection de IL-21 dans des échantillons de Humain. Il a été validé pour WB et IHC (p).

Aperçu rapide pour IL-21 anticorps (Center) (ABIN302822)

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-21 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-IL-21 anticorps

Épitope: Center

Specificité: This antibody is specific to Interleukin-21 (IL21).

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide corresponding to 15 amino acids near the center of IL-21 precursor.

Information d'application

Indications d'application: Western Blot: 0.5-1.0 μg/mL. Immunohistochemistry on Paraffin Sections: 5 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: DO NOT FREEZE!!

Stock: 4 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C.

Détails sur IL-21

Antigène: IL-21 (IL21) (Interleukin 21 (IL21))

Autre désignation: Interleukin-21 / IL21

Sujet: A novel cytokine was recently identified in Human and Mouse and designated IL-21, which has significant homology to IL-2, IL-4, and IL-15. The receptor for IL-21 (IL-21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL-21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL-21 signaling. IL-21 and its receptor activate JAK-STAT signaling pathway. IL-21 is expressed in activated T cells, and HL-60 and THP-1 cell lines. IL-21 plays a role in the proliferation and maturation of NK, B and T cell populations.Synonyms: IL-21, Za11

ID gène: 59067

NCBI Accession: NP_001193935

UniProt: Q9HBE4

Pathways: Signalistation JAK/STAT, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response