Angiostatin anticorps (AA 103-352)

N° du produit ABIN3028464

Cet anticorps anti-Angiostatin Polyclonal Lapin (ABIN3028464) détecte spécifiquement Angiostatin dans WB, ELISA et IHC (p). L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour Angiostatin anticorps (AA 103-352) (ABIN3028464)

Antigène: Angiostatin (ANG)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiostatin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-Angiostatin anticorps

Épitope: AA 103-352

Fonction: Angiostatin K1-3 Antibody

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 103-352) was used as the immunogen for this Angiostatin K1-3 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Angiostatin K1-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the Angiostatin K1-3 antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Angiostatin

Antigène: Angiostatin (ANG)

Autre désignation: Angiostatin K1-3

Sujet: Ang K1-3 is a proteolytic fragment of Plasminogen. It is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity (ED50=70nM) relative to kringles 1-4 (ED50 = 135nM).

UniProt: P00747

Pathways: Lipid Metabolism