Angiostatin anticorps (AA 103-352)

N° du produit ABIN3028464

Détail du produit anti-Angiostatin anticorps

Antigène: Angiostatin (ANG)

Épitope: AA 103-352

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Angiostatin est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 103-352) was used as the immunogen for this Angiostatin K1-3 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Angiostatin K1-3 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA: 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Angiostatin K1-3 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Angiostatin

Antigène: Angiostatin (ANG)

Autre désignation: Angiostatin K1-3 (ANG Produits)

Synonymes: anticorps ALS9, anticorps HEL168, anticorps RNASE4, anticorps RNASE5, anticorps LPA, anticorps AI649309, anticorps Pg, anticorps Ab1-346, anticorps AI385586, anticorps Ang1, anticorps Rnase5, anticorps Rnase5a, anticorps angiogenin, anticorps plasminogen, anticorps angiogenin, ribonuclease, RNase A family, 5, anticorps ANG, anticorps PLG, anticorps Plg, anticorps Ang

Sujet: Ang K1-3 is a single, non-glycosylated polypeptide chain containing 259 amino acids. It represents a proteolytic fragment of plasminogen containing the first three kringle structures. Ang K1-3 reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. It displays increased inhibitory activity(ED50=70nM) relative to kringles 1-4(ED50 = 135nM).

UniProt: P00747

Pathways: Lipid Metabolism