Alkaline Phosphatase anticorps (N-Term)

N° du produit ABIN3029906

L’anticorps Lapin Polyclonal anti-Alkaline Phosphatase a été validé pour WB. Il convient pour détecter Alkaline Phosphatase dans des échantillons de Humain.

Aperçu rapide pour Alkaline Phosphatase anticorps (N-Term) (ABIN3029906)

Antigène: Alkaline Phosphatase (ALP)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Alkaline Phosphatase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Alkaline Phosphatase anticorps

Épitope: N-Term

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human ALPL (DQAQETLKYALELQK) was used as the immunogen for this tissue-nonspecific Alkaline Phosphatase antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the Alkaline Phosphatase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Alkaline Phosphatase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Alkaline Phosphatase

Antigène: Alkaline Phosphatase (ALP)

Autre désignation: Alkaline Phosphatase

Sujet: Alkaline phosphatase (ALPL) removes phosphate groups from the 5-prime end of DNA and RNA, and from proteins, at high pH . Most mammals have 4 different isozymes: placental, placental like, intestinal and non tissue specific (found in liver, kidney and bone). Tissues with particularly high concentrations of ALP include the liver, bile ducts, placenta, and bone. ALPL is the alkaline phosphatase of skin fibroblasts,the tissue-nonspecific type, and that it is active toward millimolar concentrations of the putative natural substrates phosphoethanolamine(PEA) and pyridoxal-5-prime-phosphate(PLP). ALPL gene exists in single copy in the haploid genome and is composed of 12 exons distributed over more than 50 kb.Damaged or diseased tissue releases enzymes into the blood, so serum ALP measurements can be abnormal in many conditions, including bone disease and liver disease.

UniProt: P05186