APOE anticorps (AA 19-317)

N° du produit ABIN3029996

L’anticorps Lapin Polyclonal anti-APOE a été validé pour WB, ELISA et IHC (p). Il convient pour détecter APOE dans des échantillons de Humain.

Aperçu rapide pour APOE anticorps (AA 19-317) (ABIN3029996)

Antigène: APOE (Apolipoprotein E (APOE))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp APOE est non-conjugé

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-APOE anticorps

Épitope: AA 19-317

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 19-317) was used as the immunogen for this ApoE antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the ApoE antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,ELISA (Capture, recombinant human protein): 0.1-0.5 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the ApoE antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur APOE

Antigène: APOE (Apolipoprotein E (APOE))

Autre désignation: ApoE

Sujet: Apolipoprotein E, also known as AD2 or LPG, is a major apoprotein of the chylomicron. It binds to a specific liver and peripheral cell receptor, and is essential for the normal catabolism of triglyceride-rich lipoprotein constituents. The gene maps to chromosome 19 in a cluster with the related apolipoprotein C1 and C2 genes. Mutations in ApoE result in familial dysbetalipoproteinemia, or type III hyperlipoproteinemia (HLP III), in which increased plasma cholesterol and triglycerides are the consequence of impaired clearance of chylomicron and VLDL remnants. Alternative splicing results in multiple ApoE transcript variants.

ID gène: 348

Pathways: Regulation of Cell Size, Lipid Metabolism