CD40 anticorps (AA 1-360)

N° du produit ABIN3030398

L’anticorps Lapin Polyclonal anti-CD40 a été validé pour WB et IHC (p). Il convient pour détecter CD40 dans des échantillons de Humain et Rat.

Aperçu rapide pour CD40 anticorps (AA 1-360) (ABIN3030398)

Antigène: CD40

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD40 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-CD40 anticorps

Épitope: AA 1-360

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 1-360) was used as the immunogen for this p50 antibody.

Isotype: IgG

Information d'application

Indications d'application: Titration of the p50 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: The p50 antibody can be stored at 4°C to -20°C. After reconstitution, aliquot and store at -20°C. Avoid repeat freeze/thaws.

Détails sur CD40

Antigène: CD40

Autre désignation: p50

Sujet: Nuclear factor NF-kappa-B p105/p50, also called EBP-1 is a protein that in humans is encoded by the NFKB1 gene. By fluorescence in situ hybridization, the gene was assigned to human chromosome 4q24. NFKB1 is a pleiotropic transcription factor present in almost all cell types and is the endpoint of a series of signal transduction events that are initiated by a vast array of stimuli related to many biological processes such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NFKB1 appears to have dual functions such as cytoplasmic retention of attached NFKB1 proteins by p105 and generation of p50 by a cotranslational processing.

ID gène: 4790

Pathways: Signalisation NF-kappaB, Cellular Response to Molecule of Bacterial Origin, M Phase, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints