RAD51 anticorps (AA 1-258)

N° du produit ABIN3030760

Détail du produit anti-RAD51 anticorps

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Épitope: AA 1-258

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAD51 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 1-258) was used as the immunogen for this Rad51 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Rad51 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Rad51 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RAD51

Antigène: RAD51 (DNA Repair Protein Homolog 1 (RAD51))

Autre désignation: Rad51 (RAD51 Produits)

Synonymes: anticorps BRCC5, anticorps HRAD51, anticorps HsRad51, anticorps HsT16930, anticorps MRMV2, anticorps RAD51A, anticorps RECA, anticorps CRAD51, anticorps wu:fb38e12, anticorps zgc:77754, anticorps RGD1563603, anticorps ATRAD51, anticorps F22D1.20, anticorps F22D1_20, anticorps RAS associated with diabetes protein 51, anticorps AV304093, anticorps Rad51a, anticorps Reca, anticorps brcc5, anticorps rad51, anticorps rad51a, anticorps reca, anticorps xrad51, anticorps RAD51 recombinase, anticorps RAS associated with diabetes protein 51, anticorps RAD51 recombinase L homeolog, anticorps RAD51, anticorps rad51, anticorps Rad51, anticorps rad51.L

Sujet: DNA repair protein RAD51 homolog 1, also known as RAD51A, is a human gene. The Rad51 gene, HsRAD51, is a homolog of RecA of Escherichia coli and functions in recombination and DNA repair. BRCA1 and BRCA2 proteins form a complex with Rad51, and these genes are thought to participate in a common DNA damage response pathway associated with the activation of homologous recombination and double-strand break repair. It is found to interact with < a href=../search_result.php?search_txt=brca>BRCA1 and BRCA2, which may be important for the cellular response to DNA damage. BRCA2 is shown to regulate both the intracellular localization and DNA-binding ability of this protein. Loss of these controls following BRCA2 inactivation may be a key event leading to genomic instability and tumorigenesis.

ID gène: 5888

Pathways: Réparation de l'ADN