DRD5 anticorps (C-Term)

N° du produit ABIN3030769

Cet anticorps Lapin Polyclonal détecte spécifiquement DRD5 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour DRD5 anticorps (C-Term) (ABIN3030769)

Antigène: DRD5 (Dopamine Receptor D5 (DRD5))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DRD5 anticorps

Épitope: C-Term

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of mouse DRD5 (LISYNQDTVFHREIAAAYVH) was used as the immunogen for this Dopamine Receptor D5 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Dopamine Receptor D5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Dopamine Receptor D5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur DRD5

Antigène: DRD5 (Dopamine Receptor D5 (DRD5))

Autre désignation: Dopamine Receptor D5

Sujet: D(1B) dopamine receptor D5, also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.

UniProt: Q8BLD9

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity