Connexin 43/GJA1 anticorps (AA 351-367)

N° du produit ABIN3031019

L’anticorps anti-Connexin 43/GJA1 Polyclonal Lapin est utilisé pour la détection de Connexin 43/GJA1 dans des échantillons de Humain, Souris et Rat. Il a été validé pour WB, IHC (p) et IHC (fro).

Aperçu rapide pour Connexin 43/GJA1 anticorps (AA 351-367) (ABIN3031019)

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Connexin 43/GJA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Connexin 43/GJA1 anticorps

Épitope: AA 351-367

Fonction: Cx43 Antibody / Connexin 43

Purification: Antigen affinity

Immunogène: Amino acids 351-367 (HELQPLAIVDQRPSSRA-human) were used as the immunogen for this Cx43 antibody (100% conserved in mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: Titration of the Cx43 antibody may be required due to differences in protocols and secondary/substrate sensitivity.

1.Suitability for western blot testing of human samples is still being determined.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: The lyophilized Cx43 antibody can be stored at 4oC to -20oC. After reconstitution, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur Connexin 43/GJA1

Antigène: Connexin 43/GJA1 (GJA1) (Gap Junction Protein, alpha 1, 43kDa (GJA1))

Autre désignation: Cx43

Sujet: Connexin 43 (Cx43), also called GAP Junction Protein, alpha, is a member of the connexin gene family and is abundantly expressed in the heart and liver. Connexin 43, the major protein of gap junctions in the heart, is targeted by several protein kinases that regulate myocardial cell-cell coupling. Cx43 also plays a critical role in the physiology of hearing, presumably by participating in the recycling of potassium to the cochlear endolymph.

UniProt: P17302

Pathways: Signalisation MAPK, Myometrial Relaxation and Contraction, Cell-Cell Junction Organization