GRIA4 anticorps (AA 176-350)

N° du produit ABIN3031063

Cet anticorps Lapin Polyclonal détecte spécifiquement GRIA4 dans WB. Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour GRIA4 anticorps (AA 176-350) (ABIN3031063)

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GRIA4 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-GRIA4 anticorps

Épitope: AA 176-350

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 176-350) was used as the immunogen for this GLUR4 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the GLUR4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the GLUR4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur GRIA4

Antigène: GRIA4 (Glutamate Receptor, Ionotropic, AMPA 4 (GRIA4))

Autre désignation: GLUR4 (Glutamate Receptor 4)

Sujet: Glutamate receptor 4 also named GRIA4 or GLUR4, is a protein that in humans is encoded by the GRIA4 gene. It is mapped to 11q22.3. This gene is a member of a family of L-glutamate-gated ion channels that mediate fast synaptic excitatory neurotransmission. These channels are also responsive to the glutamate agonist, alpha-amino-3-hydroxy-5-methyl-4-isoxazolpropionate (AMPA). Some haplotypes of this gene show a positive association with schizophrenia. Additionally, glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes composed of multiple subunits, arranged to form ligand-gated ion channels.

ID gène: 2893

Pathways: Signalisation PI3K-Akt