RAD23B anticorps (AA 163-176)
Aperçu rapide pour RAD23B anticorps (AA 163-176) (ABIN303137)
Antigène
Voir toutes RAD23B AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 163-176
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Specificité
- Recognizes RAD23B (163-176).
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Réactivité croisée (Details)
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Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human. -
Purification
- Immunoaffinity Chromatography.
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Immunogène
- Synthetic peptide corresponding to amino acids 163-176 of Human HR23B protein.
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Indications d'application
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ELISA (1/2000-1/10000). Western Blot (1/500-1/2000). Immunofluorescence. Immunohistochemistry on Paraffin Sections (2.5 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. -
Restrictions
- For Research Use only
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Concentration
- 1.1 mg/mL
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Buffer
- 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
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- RAD23B (RAD23 Homolog B (RAD23B))
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Autre désignation
- RAD23B
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Sujet
- HR23B (also known as UV excision repair protein RAD23 homolog B, XP-C repair complementing complex 58 kDa protein and p58) is one of two human homologs of Saccharomyces cerevisiae Rad23 (hHR23A and hHR23B), a protein involved in nucleotide excision repair (NER). This protein was shown to interact with, and elevate the nucleotide excision activity of 3-methyladenine-DNA glycosylase (MPG), which suggested a role in DNA damage recognition in base excision repair. This protein contains an N-terminal ubiquitin-like domain, which was reported to interact with 26S proteasome, as well as with ubiquitin protein ligase E6AP, and thus suggests that this protein may be involved in the ubiquitin mediated proteolytic pathway in cells.Synonyms: HR23B, UV excision repair protein RAD23 homolog B, XP-C repair-complementing complex 58 kDa protein
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ID gène
- 5887
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NCBI Accession
- NP_002865
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UniProt
- P54727
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Pathways
- Réparation de l'ADN
Antigène
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