DREAM anticorps (N-Term)
Aperçu rapide pour DREAM anticorps (N-Term) (ABIN3031577)
Antigène
Voir toutes DREAM (KCNIP3) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
-
-
Épitope
- N-Term
-
Purification
- Antigen affinity
-
Immunogène
- An amino acid sequence from the N-terminus of human Calsenilin (MQPAKEVTKASDGSLL) was used as the immunogen for this CSEN antibody.
-
Isotype
- IgG
-
-
-
-
Indications d'application
- The stated application concentrations are suggested starting amounts. Titration of the CSEN antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
-
Restrictions
- For Research Use only
-
-
-
Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
-
Stock
- -20 °C
-
Stockage commentaire
- After reconstitution, the CSEN antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
-
-
- DREAM (KCNIP3) (Kv Channel Interacting Protein 3, Calsenilin (KCNIP3))
-
Autre désignation
- CSEN
-
Sujet
- Calsenilin (CSEN) is a calcium-dependent transcriptional repressor that is highly expressed in central nervous system, thyroid gland, testis, thymus, and immune cells. The KCNIP3 gene encodes a member of the family of voltage-gated potassium(Kv) channel-interacting proteins, which belong to the neuronal calcium sensor family of proteins. Calsenilin functions as a calcium-regulated transcriptional repressor, and interacts with presenilins. KCNIP3-regulated genes have a critical function in Ig subclass production and proliferation in B lymphocytes. It has been shown to interact with PSEN1 and PSEN2.
-
UniProt
- Q9Y2W7
Antigène
-