Lamin B2 anticorps (AA 580-597)

N° du produit ABIN3031588

Cet anticorps Lapin Polyclonal détecte spécifiquement Lamin B2 dans WB, IHC (p) et IHC (fro). Il présente une réactivité envers Humain, Souris et Rat.

Aperçu rapide pour Lamin B2 anticorps (AA 580-597) (ABIN3031588)

Antigène: Lamin B2 (LMNB2)

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Détail du produit anti-Lamin B2 anticorps

Épitope: AA 580-597

Purification: Antigen affinity

Immunogène: Amino acids 580-597 (EEDLFHQQGDPRTTSRGC) were used as the immunogen for this Lamin B2 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: Titration of the Lamin B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: The lyophilized Lamin B2 antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Lamin B2

Antigène: Lamin B2 (LMNB2)

Autre désignation: Lamin B2

Sujet: Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, was generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.

UniProt: Q03252

Pathways: Apoptose, Caspase Cascade in Apoptosis