Lamin B2 anticorps (AA 580-597)

N° du produit ABIN3031588

Détail du produit anti-Lamin B2 anticorps

Antigène: Lamin B2 (LMNB2)

Épitope: AA 580-597

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Lamin B2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Purification: Antigen affinity

Immunogène: Amino acids 580-597 (EEDLFHQQGDPRTTSRGC) were used as the immunogen for this Lamin B2 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: Titration of the Lamin B2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,IHC (Frozen): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: The lyophilized Lamin B2 antibody can be stored at 4°C. After reconstitution, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Lamin B2

Antigène: Lamin B2 (LMNB2)

Autre désignation: Lamin B2 (LMNB2 Produits)

Synonymes: anticorps lmnb2-a, anticorps LMNB2, anticorps lmn2, anticorps lamb2, anticorps Lamin-L(II), anticorps LOC100136040, anticorps im:7142331, anticorps lamin, anticorps wu:fb94e05, anticorps wu:fb95e12, anticorps wu:fc15d06, anticorps wu:fc49h03, anticorps lamin-b2, anticorps lmnb2, anticorps LAMB2, anticorps LMN2, anticorps RGD1563803, anticorps lamin B2 S homeolog, anticorps lamin B2, anticorps lamin B2 L homeolog, anticorps lmnb2.S, anticorps LMNB2, anticorps lmnb2, anticorps lmnb2.L, anticorps Lmnb2

Sujet: Lamin B2, also called LMNB2, is a protein associated with laminopathies. The LMNB2 gene is mapped to the G-negative subtelomeric band p13.3 of chromosome 19 by in situ hybridization. Model organisms have been used in the study of Lamin B2 function. A conditional knockout mouse line, called Lmnb2, was generated as part of the International Knockout Mouse Consortium program-a high-throughput mutagenesis project to generate and distribute animal models of disease to interested scientists. A highly sensitive procedure about mapping the start site of DNA replication in a 13.7-kb region of human chromosome 19 coding for lamin B2 is developed for the identification of the origin of bidirectional DNA synthesis in single-copy replicons of mammalian cells.

UniProt: Q03252

Pathways: Apoptose, Caspase Cascade in Apoptosis