MFN2 anticorps (AA 601-757)

N° du produit ABIN3031819

Cet anticorps Lapin Polyclonal détecte spécifiquement MFN2 dans WB. Il présente une réactivité avec des échantillons de Humain, Souris et Rat.

Aperçu rapide pour MFN2 anticorps (AA 601-757) (ABIN3031819)

Antigène: MFN2 (Mitofusin 2 (MFN2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFN2 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-MFN2 anticorps

Épitope: AA 601-757

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 601-757) was used as the immunogen for this MFN2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the MFN2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the MFN2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur MFN2

Antigène: MFN2 (Mitofusin 2 (MFN2))

Autre désignation: MFN2

Sujet: Mitofusin-2 is a protein that in humans is encoded by the MFN2 gene. It is mapped to chromosome 1 and encodes a 757-amino acid protein that contains an ATP/GTP-binding site motif. This gene is expressed in many tissues and cell lines such as brain and KG-1 with the highest expression in heart and skeletal muscle. It has been found that MFN2 triggers mitochondrial energization, at least in part, by regulating OXPHOS expression through signals that are independent of its role as a mitochondrial fusion protein. And it contributes to the maintenance and operation of the mitochondrial network. Axonal CMT type 2A and autosomal dominant HMSN VI are caused by MFN2 and mutations of, which emphasizes its important role of mitochondrial function for both optic atrophies and peripheral neuropathies.

ID gène: 9927

Pathways: Skeletal Muscle Fiber Development