MUC5AC anticorps (AA 4848-5030)
Aperçu rapide pour MUC5AC anticorps (AA 4848-5030) (ABIN3031872)
Antigène
Voir toutes MUC5AC AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 4848-5030
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Purification
- Antigen affinity
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Immunogène
- Human partial recombinant protein (4848-5030) was used as the immunogen for this MUC5AC antibody.
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Isotype
- Ig Fraction
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the MUC5AC antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the MUC5AC antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))
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Autre désignation
- MUC5AC Mucin-5AC
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Sujet
- Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease(COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. It is also a direct and critical mediator of resistance during intestinal nematode infection.
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ID gène
- 4586
Antigène
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