MUC5AC anticorps (AA 4848-5030)

N° du produit ABIN3031872

Cet anticorps anti-MUC5AC Polyclonal Lapin (ABIN3031872) détecte spécifiquement MUC5AC dans IHC (p). L’anticorps est réactif avec des échantillons de Humain et Rat.

Aperçu rapide pour MUC5AC anticorps (AA 4848-5030) (ABIN3031872)

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MUC5AC est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Détail du produit anti-MUC5AC anticorps

Épitope: AA 4848-5030

Fonction: MUC5AC Antibody / Mucin-5AC

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (4848-5030) was used as the immunogen for this MUC5AC antibody.

Isotype: Ig Fraction

Information d'application

Indications d'application: The stated application concentrations are suggested starting points. Titration of the MUC5AC antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: 4 °C,-20 °C

Stockage commentaire: After reconstitution, the MUC5AC antibody can be stored for up to one month at 4oC. For long-term, aliquot and store at -20oC. Avoid repeated freezing and thawing.

Détails sur MUC5AC

Antigène: MUC5AC (Mucin 5AC, Oligomeric Mucus/gel-Forming (MUC5AC))

Autre désignation: MUC5AC

Sujet: Mucin-5AC is a protein that in humans is encoded by the MUC5AC gene. It is mapped to 11p15.5. MUC5AC is highly expressed in adult trachea and stomach. This gene has been linked to mucus hypersecretion in the pulmonary tracts and associated to chronic obstructive pulmonary disease (COPD). It has been showed that activation of the NF-kappa-B signaling pathway by inflammatory cytokine TNF-alpha upregulated MUC5AC mRNA expression nearly 6-fold. It is also a direct and critical mediator of resistance during intestinal nematode infection.