NME2 anticorps (AA 137-152)

N° du produit ABIN3032112

Cet anticorps anti-NME2 est un anticorps Lapin Polyclonal détectant NME2 dans WB, IHC (p) et ICC. Adapté pour Humain, Souris et Rat.

Aperçu rapide pour NME2 anticorps (AA 137-152) (ABIN3032112)

Antigène: NME2 (Nucleoside diphosphate kinase B (NME2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NME2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Détail du produit anti-NME2 anticorps

Épitope: AA 137-152

Purification: Antigen affinity

Immunogène: Amino acids 137-152 (EELVDYKSCAHDWVYE-human) were used as the immunogen for this NME2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the NME2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the NME2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur NME2

Antigène: NME2 (Nucleoside diphosphate kinase B (NME2))

Autre désignation: NME2

Sujet: NME2 (NME/NM23 nucleoside diphosphate kinase 2) also called non-metastatic cells 2, protein (NM23B) expressed in, NM23-H2, NM23B or NDPKB, is identical to the beta subunit of human erythrocyte NDP kinase. Using Northern blot analysis, Masse et al.(2002) detected high expression of mouse NME2, which they called nm23-M2, in heart, liver, and kidney, with intermediate expression in skeletal muscle. In situ hybridization of 15-day postcoitum mouse embryos showed ubiquitous expression. The mouse and human genes contain 5 exons and span about 6.0 kb. The NME2 gene is mapped on 17q21.33. Srivastava et al.(2006) concluded that histidine phosphorylation regulates KCa3.1 channel activity and that NME2 is critical to the channel activity and the activation of CD4 T cells.

UniProt: P22392