NLRC4 anticorps (C-Term)

N° du produit ABIN303226

Détail du produit anti-NLRC4 anticorps

Antigène: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp NLRC4 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic Peptide corresponding to amino acids near the C-terminus of Human Ipaf.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (5 μg/mL). Immunocytochemistry. Western Blot (0.5-2 μg/mL).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C to -70 °C for longer. Dilute only prior to immediate use.

Détails sur NLRC4

Antigène: NLRC4 (NLR Family, CARD Domain Containing 4 (NLRC4))

Autre désignation: NLRC4 (NLRC4 Produits)

Synonymes: anticorps CARD12, anticorps CLAN, anticorps CLAN1, anticorps CLANA, anticorps CLANB, anticorps CLANC, anticorps CLAND, anticorps CLR2.1, anticorps IPAF, anticorps 9530011P19Rik, anticorps Card12, anticorps NLR family CARD domain containing 4, anticorps NLR family, CARD domain containing 4, anticorps NLRC4, anticorps Nlrc4

Sujet: Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands. Cell death signals are transduced by death domain containing adaptor molecules and proteases including several members of the caspase family. Another family of proteins that functions as a critical regulator of apoptosis and NF-kB signaling pathways is the CED-4/Apaf-1 (apoptosis protein activating factor-1) protein family. Ipaf (ICE protease activating factor) is a CED-4/Apaf-1 family member that activates caspase-1/ICE and can induce apoptosis in human cells in a caspase-1 dependent manner. Ipaf and caspase-1 are thought to interact with each other through the association of the Ipaf amino-terminal CARD (caspase recruitment domain) and amino-terminal CARD of caspase-1.Synonyms: CARD12, CLAN, CLAN1, IPAF, NLR family CARD domain-containing protein 4

ID gène: 58484

NCBI Accession: NP_001186067

UniProt: Q9NPP4

Pathways: Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Inflammasome