RAB8A anticorps (C-Term)

N° du produit ABIN3032426

Détail du produit anti-RAB8A anticorps

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp RAB8A est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Rab8A (KAKMDKKLEGNSPQ) was used as the immunogen for this Rab8 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Rab8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Rab8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur RAB8A

Antigène: RAB8A (RAB8A, Member RAS Oncogene Family (RAB8A))

Autre désignation: Rab8 (RAB8A Produits)

Synonymes: anticorps rab8A, anticorps DDBDRAFT_0206521, anticorps DDBDRAFT_0214885, anticorps DDB_0206521, anticorps DDB_0214885, anticorps HSH2D, anticorps mel, anticorps rab8, anticorps c-mel, anticorps MEL, anticorps RAB8, anticorps zgc:162699, anticorps AA409338, anticorps Mel, anticorps Rab8, anticorps rab8A protein, anticorps Rab GTPase, anticorps RAB8A, member RAS oncogene family, anticorps RAB8A, member RAS oncogene family S homeolog, anticorps rab8A, anticorps RAB8A, anticorps rab8a, anticorps rab8a.S, anticorps Rab8a

Sujet: Ras-related protein Rab8 is a protein that in humans is encoded by the RAB8A gene. The protein encoded by this gene is a member of the RAS superfamily which are small GTP/GDP-binding proteins with an average size of 200 amino acids. The RAS-related proteins of the RAB/YPT family may play a role in the transport of proteins from the endoplasmic reticulum to the Golgi and the plasma membrane. Rab8 regulates cilia assembly by targeting and promoting fusion of vesicles near the ciliary membrane. This gene requires CEP290 for centrosome localization and that CEP290 regulates entry of Rab8 into the cilium during assembly of this organelle. It has been shown to interact with Optineurin and MAP4K2.

UniProt: P61006

Pathways: M Phase, Regulation of long-term Neuronal Synaptic Plasticity, SARS-CoV-2 Protein Interactome