DCLRE1C anticorps (AA 482-495)

N° du produit ABIN303343

Cet anticorps Chèvre Polyclonal détecte spécifiquement DCLRE1C dans WB, IHC (p) et EIA. Il présente une réactivité avec des échantillons de Humain.

Aperçu rapide pour DCLRE1C anticorps (AA 482-495) (ABIN303343)

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Reactivité: Humain

Hôte: Chèvre

Clonalité: Polyclonal

Conjugué: Cet anticorp DCLRE1C est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Détail du produit anti-DCLRE1C anticorps

Épitope: AA 482-495

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic Peptide corresponding to aa 482-495 of Human ARTEMIS (DCLRE1C DNA cross- link repair 1C).

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (1.25-2.5 μg/mL). Western Blot (1/500-1/2000). ELISA (1/10000-1/20000).
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 with 0.01 % (w/v) Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid cycles of freezing and thawing.

Stock: -20 °C

Stockage commentaire: Store the antibody (in aliquots) at-20 °C. Dilute only prior to immediate use.

Détails sur DCLRE1C

Antigène: DCLRE1C (DNA Cross-Link Repair 1C (DCLRE1C))

Autre désignation: Artemis

Sujet: Human Artemis is a newly identified 78.4 kDa, novel DNA double-strand break repair/v(d)j recombination protein. This gene is located at human chromosome 10. Artemis has a role in T and B lymphocyte immunodeficiency and in predisposition to lymphoma through the NHEJ pathway of DNA repair. DNA-PKcs regulates Artemis by both phosphorylation and complex formation to permit enzymatic activities that are critical for the hairpin-opening step of V(D)J recombination and for the 5' and 3' overhang processing in non-homologous DNA end joining.Synonyms: A-SCID protein, ASCID, DCLRE1C, DNA cross-link repair 1C protein, SCIDA, SNM1-like protein, SNM1C

ID gène: 64421

NCBI Accession: NP_001029027

UniProt: Q96SD1

Pathways: Réparation de l'ADN