HLAG anticorps
Aperçu rapide pour HLAG anticorps (ABIN3038629)
Antigène
Voir toutes HLAG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Specificité
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The antibody 87G recognizes both membrane-bound and soluble forms of HLA-G (HLA-G1 and HLA-G5). HLA-G belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of trophoblast cells.
The antibody 87G blocks interaction of HLA-G with inhibitory receptors. -
Purification
- Purified from hybridoma culture supernatant by protein-A affinity chromatography
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Immunogène
- HLA-B27 transgenic mice were imunized with H-2 identical murine cells transfected with and expressing genes encoding HLA-G and Human beta2-microglobulin.
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Isotype
- IgG2a
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Indications d'application
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Format
- Liquid
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Buffer
- Azide free phosphate buffered saline (PBS), approx. pH 7.4, 0.2 μm filter sterilized. Endotoxin level is less than 0.01 EU/μg of the protein, as determined by the LAL test.
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Agent conservateur
- Azide free
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Stock
- 4 °C
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Stockage commentaire
- Store at 2-8°C. Do not freeze.
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- HLAG (HLA Class I Histocompatibility Antigen, alpha Chain G (HLAG))
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Autre désignation
- HLA-G
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ID gène
- 3135
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Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Cancer Immune Checkpoints, Human Leukocyte Antigen (HLA) in Adaptive Immune Response
Antigène
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