Glucose-6-Phosphate Dehydrogenase anticorps (AA 315-515)

N° du produit ABIN3042413

L’anticorps Lapin Polyclonal anti-Glucose-6-Phosphate Dehydrogenase a été validé pour WB. Il convient pour détecter Glucose-6-Phosphate Dehydrogenase dans des échantillons de Humain et Souris. Il y a 1 publication disponible.

Aperçu rapide pour Glucose-6-Phosphate Dehydrogenase anticorps (AA 315-515) (ABIN3042413)

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glucose-6-Phosphate Dehydrogenase est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-Glucose-6-Phosphate Dehydrogenase anticorps

Épitope: AA 315-515

Fonction: Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband®

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Glucose 6 Phosphate Dehydrogenase/G6PD Antibody Picoband® (ABIN3042413). Tested in WB applications. This antibody reacts with Human;Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Mouse
1. Aster J, Kumar V, Robbins SL, Abbas AK, Fausto N, Cotran RS (2010). Robbins and Cotran pathologic basis of disease. Saunders/Elsevier. pp. Kindle Locations 33340-33341. 2. Takizawa, T., Huang, I.-Y., Ikuta, T., Yoshida, A. Human glucose-6-phosphate dehydrogenase: primary structure and cDNA cloning. Proc. Nat. Acad. Sci. 83: 4157-4161, 1986.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.01 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-Glucose-6-Phosphate Dehydrogenase (ABIN3042413)

Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." dans: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).

Détails sur Glucose-6-Phosphate Dehydrogenase

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Autre désignation: G6PD

Sujet:

Synonyms: Glucose-6-phosphate 1-dehydrogenase,G6PD,1.1.1.49,G6PD,

Tissue Specificity: Isoform Long is found in lymphoblasts, granulocytes and sperm.

Background: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

Sequence Similarities: Belongs to the glucose-6-phosphate dehydrogenase family.

Poids moléculaire: 59 kDa

ID gène: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones