Glucose-6-Phosphate Dehydrogenase anticorps (AA 315-515)

N° du produit ABIN3042413

Détail du produit anti-Glucose-6-Phosphate Dehydrogenase anticorps

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Épitope: AA 315-515

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Glucose-6-Phosphate Dehydrogenase est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Glucose-6-phosphate 1-dehydrogenase(G6PD) detection. Tested with WB in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Glucose-6-phosphate 1-dehydrogenase(G6PD) detection. Tested with WB in Human.
Gene Name: glucose-6-phosphate dehydrogenase
Protein Name: Glucose-6-phosphate 1-dehydrogenase

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human G6PD recombinant protein (Position: E315-L515). Human G6PD shares 95% and 96% amino acid (aa) sequences identity with mouse and rat G6PD, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for G6PD is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-Glucose-6-Phosphate Dehydrogenase (ABIN3042413)

Hu, Zhang, Tang, Su, Li, Chen, Zhang, Cai, Zhu: "Variant G6PD levels promote tumor cell proliferation or apoptosis via the STAT3/5 pathway in the human melanoma xenograft mouse model." dans: BMC cancer, Vol. 13, Issue 1, pp. 251, (2014) (PubMed).

Détails sur Glucose-6-Phosphate Dehydrogenase

Antigène: Glucose-6-Phosphate Dehydrogenase (G6PD)

Autre désignation: G6PD (G6PD Produits)

Synonymes: anticorps G6PD1, anticorps g6pd, anticorps G6pd, anticorps G6pdx, anticorps g6pdh, anticorps g6pd2, anticorps fj78b06, anticorps wu:fj78b06, anticorps si:dkey-90a13.8, anticorps BA3433, anticorps CORTRD1, anticorps G6PDH, anticorps GDH, anticorps G28A, anticorps G6PD, anticorps Gpdx, anticorps glucose-6-phosphate dehydrogenase, anticorps glucose-6-phosphate 1-dehydrogenase, anticorps glucose-6-phosphate 1-dehydrogenase (G6PD), anticorps glucose-6-P dehydrogenase, anticorps glucose-6-phosphate dehydrogenase L homeolog, anticorps glucose-6-phosphate 1-dehydrogenase Zwf, anticorps hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase, anticorps glucose-6-phosphate dehydrogenase X-linked, anticorps G6PD, anticorps g6pd, anticorps g6pD, anticorps zwf, anticorps LOC100120232, anticorps LACBIDRAFT_188936, anticorps G6pd, anticorps g6pd.L, anticorps CNG03280, anticorps Tb10.70.5200, anticorps H6PD, anticorps G6pdx, anticorps H6pd

Sujet: Glucose-6-phosphate dehydrogenase, also known as G6PD or G6PDH, is an enzyme that in humans is encoded by the G6PD gene. It is mapped to Xq28. G6PD plays a key role in the production of ribose 5-phosphate and the generation of NADPH in the hexose monophosphate pathway. Because this pathway is the only NADPH-generation process in mature red cells, which lack the citric adid cycle, a genetic deficiency of G6PD is often associated with adverse physiologic effects. It has been found that aldosterone decreased G6PD expression and activity, resulting in increased oxidant stress and decreased nitric oxide levels, similar to what is observed in G6PD-deficient endothelial cells.

Synonyms: G6PD antibody|G6PD_HUMAN antibody|G6PD1 antibody|G6pdx antibody|Glucose 6 phosphate 1 dehydrogenase antibody|Glucose 6 phosphate dehydrogenase antibody|Glucose 6 phosphate dehydrogenase, G6PD antibody|Glucose-6-phosphate 1-dehydrogenase antibody|MET19 antibody|POS10 antibody|Zwf1p antibody

ID gène: 2539

UniProt: P11413

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones