GFRA1 anticorps (AA 25-227)

N° du produit ABIN3042422

Détail du produit anti-GFRA1 anticorps

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Épitope: AA 25-227

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GFRA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for GDNF family receptor alpha-1(GFRA1) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for GDNF family receptor alpha-1(GFRA1) detection. Tested with WB, IHC-P in Human.
Gene Name: GDNF family receptor alpha 1
Protein Name: GDNF family receptor alpha-1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human GFRA1 recombinant protein (Position: D25-Q227). Human GFRA1 shares 97% amino acid (aa) sequence identity with both mouse and rat GFRA1.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for GFRA1 is approximately 0.2 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur GFRA1

Antigène: GFRA1 (GDNF Family Receptor alpha 1 (GFRA1))

Autre désignation: GFRA1 (GFRA1 Produits)

Synonymes: anticorps gdnfr, anticorps ret1l, anticorps retl1, anticorps trnr1, anticorps gdnfra, anticorps MGC122616, anticorps gfr-alpha-1, anticorps GDNFR, anticorps GDNFRA, anticorps GFR-ALPHA-1, anticorps RET1L, anticorps RETL1, anticorps TRNR1, anticorps GDNFRALPHA, anticorps GFRA1, anticorps AU042498, anticorps gfralpha1a, anticorps zgc:110129, anticorps GDNF family receptor alpha 1, anticorps glial cell line derived neurotrophic factor family receptor alpha 1, anticorps gdnf family receptor alpha 1a, anticorps gfra1, anticorps GFRA1, anticorps Gfra1, anticorps gfra1a

Sujet: GDNF family receptor alpha-1 (GFRα1), also known as the GDNF receptor or GFRA1, is a protein that in humans is encoded by the GFRA1 gene. It is mapped to chromosome 10q25.3. The protein encoded by this gene is a member of the GDNF receptor family. GFRA1 is released by neuronal cells, Schwann cells, and injured sciatic nerve. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This gene is also a candidate gene for Hirschsprung disease. Soluble GFRA1 mediates robust recruitment of RET to lipid rafts via a mechanism requiring the RET tyrosine kinase.

Synonyms: GDNF Family Receptor Alpha 1 antibody|GDNF R antibody|GDNF RA antibody|GDNF receptor alpha antibody|GDNFR alpha 1 antibody|GDNFR alpha antibody|GDNFR antibody|GDNFRA antibody|GDNFRalpha antibody|GFR alpha 1 antibody|GFR alpha1 antibody|GFR-ALPHA-1 antibody|GFRA 1 antibody|GFRA1 antibody|GFRalpha1 antibody|Glial Cell Line DErived Neurotrophic Factor Receptor Alpha antibody|Glial cell line-derived neurotrophic factor receptor alpha antibody|GPI linked anchor protein antibody|GPI-linked anchor protein antibody|MGC23045 antibody|PI linked cell surface accessory protein antibody|RET 1L antibody|RET ligand 1 antibody|RET1L antibody|RETL 1 antibody|RETL1 antibody|TGF beta related neurotrophic factor receptor 1 antibody|TGF-beta related neurotrophic factor receptor 1 antibody|TRNR 1 antibody|TRNR1 antibody

ID gène: 14585

UniProt: P56159