HSPG2 anticorps (AA 524-701)

N° du produit ABIN3042466

Détail du produit anti-HSPG2 anticorps

Antigène: HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))

Épitope: AA 524-701

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSPG2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Basement membrane-specific heparan sulfate proteoglycan core protein(HSPG2) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Basement membrane-specific heparan sulfate proteoglycan core protein(HSPG2) detection. Tested with WB, IHC-P in Human.
Gene Name: heparan sulfate proteoglycan 2
Protein Name: Basement membrane-specific heparan sulfate proteoglycan core protein

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human HSPG2 recombinant protein (Position: F524-K701). Human HSPG2 shares 86% amino acid (aa) sequence identity with mouse HSPG2.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for HSPG2 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur HSPG2

Antigène: HSPG2 (Heparan Sulfate Proteoglycan 2 (HSPG2))

Autre désignation: HSPG2 (HSPG2 Produits)

Synonymes: anticorps HSPG, anticorps PLC, anticorps PRCAN, anticorps SJA, anticorps SJS, anticorps SJS1, anticorps HSPG2, anticorps AI852380, anticorps Pcn, anticorps Plc, anticorps per, anticorps Per, anticorps heparan sulfate proteoglycan 2, anticorps perlecan (heparan sulfate proteoglycan 2), anticorps HSPG2, anticorps hspg2, anticorps Hspg2

Sujet: Perlecan (PLC) also known as HSPG2, is a protein that in humans is encoded by the HSPG2 gene. It is mapped to 1p36.12. Perlecan is highly conserved across species and the available data indicate that it has evolved from ancient ancestors by gene duplication and exonshuffling. Perlecan is a key component of the vascular extracellular matrix, here it interacts with a variety of other matrix components and helps to maintain the endothelial barrier function. It is a potent inhibitor of smooth muscle cell proliferation and is thus thought to help maintain vascular homeostasis. Perlecan can also promote growth factor (e.g., FGF2) activity and thus stimulate endothelial growth and re-generation.

Synonyms: Basement membrane specific heparan sulfate proteoglycan core protein antibody|Endorepellin (domain V region) antibody|Heparan Sulfate Proteoglycan antibody|Heparan sulfate proteoglycan of basement membrane antibody|HSPG 2 antibody|HSPG antibody|Hspg2 antibody|LG3 peptide antibody|Perlecan antibody|PGBM_HUMAN antibody|PLC antibody|Schwartz Jampel syndrome 1 (chondrodystrophic myotonia) antibody|SJA antibody|SJS antibody|SJS1 antibody

ID gène: 3339

UniProt: P98160

Pathways: Glycosaminoglycan Metabolic Process, Lipid Metabolism