IL-18 anticorps (AA 37-194)

N° du produit ABIN3042518

Détail du produit anti-IL-18 anticorps

Antigène: IL-18 (IL18) (Interleukin 18 (IL18))

Épitope: AA 37-194

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-18 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Interleukin-18(IL18) detection. Tested with WB in Rat.

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Interleukin-18(IL18) detection. Tested with WB in Rat.
Gene Name: interleukin 18(interferon-gamma-inducing factor)
Protein Name: Interleukin-18

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived rat IL-18 recombinant protein (Position: H37-S194). Rat IL-18 shares 64% and 91% amino acid (aa) sequence identity with human and mouse IL-18, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-IL-18 (ABIN3042518)

Si, Zhang, Gao, Chen, Zhao, Cheng: "Effects of IFN-? on IL-18 Expression in Pregnant Rats and Pregnancy Outcomes." dans: Asian-Australasian journal of animal sciences, Vol. 26, Issue 10, pp. 1399-405, (2014) (PubMed).

Wang, Zhang, Zhang, Xu, Fang: "Expression and localization of IL-18 in the hypothalamic-pituitary-ovarian axis of non-pregnant, pregnant, and abortive rats." dans: Journal of reproductive immunology, Vol. 92, Issue 1-2, pp. 45-53, (2011) (PubMed).

Yang, Shen, Chen, Ge: "Role of interleukin 18 in acute lung inflammation induced by gut ischemia reperfusion." dans: World journal of gastroenterology, Vol. 11, Issue 29, pp. 4524-9, (2005) (PubMed).

Détails sur IL-18

Antigène: IL-18 (IL18) (Interleukin 18 (IL18))

Autre désignation: IL18 (IL18 Produits)

Synonymes: anticorps Igif, anticorps Il-18, anticorps IL-18, anticorps IGIF, anticorps ChIL-18, anticorps IL-1g, anticorps IL1F4, anticorps IL18, anticorps interleukin 18, anticorps Il18, anticorps IL18

Sujet: Interleukin (IL)-18, also called Interferon-gamma-inducing factor (IGIF), augments natural killer (NK) activity in spleen cells. The gene encodes a precursor protein of 192 amino acids and a mature protein of 157 amino acids. IL18 is a recently discovered cytokine that modulates both T helper type 1 (Th1) and Th2 responses. IL18 is a potent proinflammatory cytokine with potential atherogenic properties. It is highly expressed in the atherosclerotic plaques compared with control normal arteries and is localized mainly in plaque macrophages.

Synonyms: Iboctadekin antibody|IFN gamma inducing factor antibody|IFN-gamma-inducing factor antibody|IGIF antibody|IL 1 gamma antibody|IL 18 antibody|IL 1g antibody|IL-1 gamma antibody|IL-18 antibody|IL1 gamma antibody|IL18 antibody|IL18 protein antibody|IL1F4 antibody|IL1g antibody|IL1gamma antibody|ILIF4 antibody|Interferon gamma inducing factor antibody|Interferon gamma-inducing factor antibody|Interleukin 1 gamma antibody|Interleukin 18 antibody|Interleukin-1 gamma antibody|Interleukin-18 antibody|Interleukin18 antibody|MGC12320 antibody

ID gène: 29197

UniProt: P97636

Pathways: Cellular Response to Molecule of Bacterial Origin, Activated T Cell Proliferation, Cancer Immune Checkpoints, Inflammasome