GM-CSF anticorps (AA 18-141)

N° du produit ABIN3042527

Détail du produit anti-GM-CSF anticorps

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Épitope: AA 18-141

Reactivité: Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GM-CSF est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Granulocyte-macrophage colony-stimulating factor(CSF2) detection. Tested with WB, IHC-P in Mouse.

Marque: Picoband™

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Granulocyte-macrophage colony-stimulating factor(CSF2) detection. Tested with WB, IHC-P in Mouse.
Gene Name: colony stimulating factor 2 (granulocyte-macrophage)
Protein Name: Granulocyte-macrophage colony-stimulating factor

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived mouse GM-CSF recombinant protein (Position: A18-K141). Mouse GM-CSF shares 54% and 70% amino acid (aa) sequences identity with human and rat GM-CSF, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, The detection limit for GM-CSF is approximately 1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-GM-CSF (ABIN3042527)

Fang, Shi, Meng, Li, Peng: "The Balance between Conventional DCs and Plasmacytoid DCs Is Pivotal for Immunological Tolerance during Pregnancy in the Mouse." dans: Scientific reports, Vol. 6, pp. 26984, (2018) (PubMed).

Détails sur GM-CSF

Antigène: GM-CSF (CSF2) (Colony Stimulating Factor 2 (Granulocyte-Macrophage) (CSF2))

Autre désignation: CSF2 (CSF2 Produits)

Synonymes: anticorps GMCSF, anticorps GM-CSF, anticorps CSF2, anticorps Csfgm, anticorps Gm-CSf, anticorps MGI-IGM, anticorps Gm-csf, anticorps Gmcsf, anticorps CSF, anticorps colony stimulating factor 2, anticorps colony stimulating factor 2 (granulocyte-macrophage), anticorps CSF2, anticorps Csf2

Sujet: GM-CSF, Granulocyte-macrophage colony-stimulating factor, is a protein secreted by macrophages, T cells, mast cells, endothelial cells, and fibroblasts. By fluorescence in situ hybridization, the GM-CSF gene is mapped to 5q31.1. GM-CSF is a cytokine that functions as a white blood cell growth factor. GM-CSF stimulates stem cells to produce granulocytes (neutrophils, eosinophils, and basophils) and monocytes. GM-CSF is an essential regulator of neutrophil function.

Synonyms: Burst Promoting Activity antibody|CMCSF antibody|Colony stimulating factor 2 (granulocyte-macrophage) antibody|Colony Stimulating Factor 2 antibody|Colony stimulating factor antibody|Colony-stimulating factor antibody|CSF 2 antibody|CSF Alpha antibody|CSF antibody|CSF2 antibody|CSF2_HUMAN antibody|Eosinophil Colony Stimulating Factor antibody|GM-CSF antibody|GMCSF antibody|Granulocyte Macrophage Colony Stimulating Factor antibody|Granulocyte-macrophage colony-stimulating factor antibody|MGC131935 antibody|MGC138897 antibody|Molgramostin antibody|Pluripoietin Alpha antibody|Sargramostim antibody

UniProt: P01587

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin