HSD17B6 anticorps (C-Term)

N° du produit ABIN3042725

Détail du produit anti-HSD17B6 anticorps

Antigène: HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))

Épitope: AA 300-317, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HSD17B6 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for 17-beta-hydroxysteroid dehydrogenase type 6(HSD17B6) detection. Tested with WB, IHC-P in Human.

Séquence: SLADYILTRS WPKPAQAV

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for 17-beta-hydroxysteroid dehydrogenase type 6(HSD17B6) detection. Tested with WB, IHC-P in Human.
Gene Name: hydroxysteroid(17-beta) dehydrogenase 6 homolog(mouse)
Protein Name: 17-beta-hydroxysteroid dehydrogenase type 6(17-beta-HSD 6/17-beta-HSD6)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human HSD17B6(300-317aa SLADYILTRSWPKPAQAV).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide, Thimerosal (Merthiolate)

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur HSD17B6

Antigène: HSD17B6 (Hydroxysteroid (17-Beta) Dehydrogenase 6 (HSD17B6))

Autre désignation: HSD17B6 (HSD17B6 Produits)

Synonymes: anticorps HSE, anticorps RODH, anticorps SDR9C6, anticorps 17betaHSD9, anticorps Hsd17b9, anticorps Rdh8, anticorps hydroxysteroid 17-beta dehydrogenase 6, anticorps hydroxysteroid (17-beta) dehydrogenase 6, anticorps HSD17B6, anticorps Hsd17b6

Sujet: Hydroxysteroid 17-beta dehydrogenase 6 is an enzyme that in humans is encoded by the HSD17B6 gene. The protein encoded by this gene has both oxidoreductase and epimerase activities and is involved in androgen catabolism. Baker ME et al point out expression of 17beta-HSDs had an important role in the early evolution of the physiological response to androgens and estrogens. Biswas and Russell concluded that 17beta-HSD6 and RoDH play opposing roles in androgen action, 17beta-HSD6 inactivates 3alpha-adiol by conversion to androsterone and RoDH activates 3alpha-adiol by conversion to dihydrotestosterone. The synthesis of an active steroid hormone by back conversion of an inactive metabolite represents a potentially important mechanism by which the steady state level of a transcriptional effector can be regulated.

Synonyms: 17-beta-HSD 6 antibody|17-beta-HSD6 antibody|17-beta-hydroxysteroid dehydrogenase type 6 antibody|3 hydroxysteroid epimerase antibody|3(alpha>beta) hydroxysteroid epimerase antibody|3(alpha>beta) hydroxysteroid epimerasel antibody|3-alpha->beta-HSE antibody|3-alpha->beta-hydroxysteroid epimerase antibody|H17B6_HUMAN antibody|HSD17B6 antibody|HSE antibody|Hydroxysteroid(17 beta) dehydrogenase 6 antibody|Hydroxysteroid(17 beta) dehydrogenase 6 homolog(mouse) antibody|Hydroxysteroid 17 beta dehydrogenase 6 antibody|NAD+ dependent 3 alpha hydroxysteroid dehydrogenase 3 hydroxysteroid epimerase antibody|NAD+ dependent 3 alpha hydroxysteroid dehydrogenase antibody|Oxidative 3 alpha hydroxysteroid dehydrogenase antibody|Oxidative 3-alpha hydroxysteroid dehydrogenase antibody|Oxidoreductase antibody|Retinol dehydrogenase antibody|RODH antibody|SDR9C6 antibody|Short chain dehydrogenase/reductase family 9C, member 6 antibody

UniProt: O14756

Pathways: Steroid Hormone Biosynthesis