IL12B anticorps (AA 23-321)

N° du produit ABIN3042735

Détail du produit anti-IL12B anticorps

Antigène: IL12B (Interleukin 12 beta (IL12B))

Épitope: AA 23-321

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12B est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Interleukin-12 subunit beta(IL12B) detection. Tested with WB in Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Interleukin-12 subunit beta(IL12B) detection. Tested with WB in Rat.
Gene Name: interleukin 12B
Protein Name: Interleukin-12 subunit beta

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived rat IL-12(p40) recombinant protein (Position: M23-S321).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, The detection limit for IL-12(p40) is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-IL12B (ABIN3042735)

Dong, Xia, Chen, Chen, Zhang: "Anti-arthritis activity of cationic materials." dans: Journal of cellular and molecular medicine, Vol. 14, Issue 7, pp. 2015-24, (2011) (PubMed).

Détails sur IL12B

Antigène: IL12B (Interleukin 12 beta (IL12B))

Autre désignation: IL12B (IL12B Produits)

Synonymes: anticorps CLMF, anticorps CLMF2, anticorps IL-12B, anticorps NKSF, anticorps NKSF2, anticorps p40, anticorps Il-12b, anticorps Il12p40, anticorps Il-12p40, anticorps Il12, anticorps IL-12p40, anticorps IL-12, anticorps IL-12 p40, anticorps il12b, anticorps il12p40.b, anticorps zgc:152789, anticorps IL-12.p40, anticorps IL12p40, anticorps IL12B, anticorps CLMF p40, anticorps interleukin 12B, anticorps interleukin 12b, anticorps interleukin 12Ba, anticorps IL12B, anticorps Il12b, anticorps il12ba

Sujet: Subunit beta of interleukin 12, also known as interleukin 12B, or IL12B, is a subunit of human interleukin 12. It is mapped to 5q33.3. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease.

Synonyms: 40 kD Subunit antibody|CLMF 2 antibody|CLMF antibody|CLMF p40 antibody|CLMF2 antibody|Cytotoxic lymphocyte maturation factor 2 antibody|Cytotoxic lymphocyte maturation factor 2 p40 antibody|Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody|IL 12 subunit p40 antibody|IL 12B antibody|IL-12 subunit p40 antibody|IL-12B antibody|IL12 subunit p40 antibody|IL12B antibody|IL12B_HUMAN antibody|Interleukin 12 beta chain antibody|Interleukin 12 p40 antibody|Interleukin 12 subunit beta antibody|Interleukin 12B antibody|Interleukin-12 subunit beta antibody|Natural killer cell stimulatory factor 2 antibody|natural killer cell stimulatory factor 40 kD subunit antibody|NK cell stimulatory factor chain 2 antibody|NKSF 2 antibody|NKSF antibody|NKSF2 antibody|p40 antibody|TcMF antibody|TSF antibody

ID gène: 64546

UniProt: Q9R278

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation