IL-13 anticorps (AA 25-146)

N° du produit ABIN3042736

Cet anticorps Lapin Polyclonal détecte spécifiquement IL-13 dans WB et ELISA. Il présente une réactivité envers Humain et a été mentionné dans 1 publication.

Aperçu rapide pour IL-13 anticorps (AA 25-146) (ABIN3042736)

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-13 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-IL-13 anticorps

Épitope: AA 25-146

Fonction: Anti-Interleukin-13 IL13 Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Interleukin-13 IL13 Antibody (ABIN3042736). Tested in ELISA, WB applications. This antibody reacts with Human. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived human IL-13 recombinant protein (Position: L25-N146). Human IL-13 shares 57% and 62% amino acid (aa) sequence identity with mouse and rat IL-13, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human
ELISA, 0.1-0.5 μg/mL, -

Commentaires:

Antibody can be supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Références pour anticorps anti-IL-13 (ABIN3042736)

Li, Li, Zuo, Ke, Yan, Wen, Zhang, Yang: "T-helper type-2 contact hypersensitivity of Balb/c mice aggravated by dibutyl phthalate via long-term dermal exposure." dans: PLoS ONE, Vol. 9, Issue 2, pp. e87887, (2014) (PubMed).

Détails sur IL-13

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Autre désignation: IL13

Sujet:

Synonyms: Interleukin-13,IL-13,IL13,NC30,

Tissue Specificity: Activated T-cells, mast cells, natural killer cells.

Background: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is a kind of cytokine secreted by many cell types, but especially T helper type 2 (Th2) cells, which is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor (IL-4Rα) and at least one of two known IL-13-specific binding chains. This gene acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Sequence Similarities: Belongs to the IL-4/IL-13 family.

Poids moléculaire: 37 kDa

ID gène: 3596

UniProt: P35225

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport