COPS5 anticorps (AA 8-334)

N° du produit ABIN3042754

Détail du produit anti-COPS5 anticorps

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Épitope: AA 8-334

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COPS5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for COP9 signalosome complex subunit 5(COPS5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for COP9 signalosome complex subunit 5(COPS5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: COP9 signalosome subunit 5
Protein Name: COP9 signalosome complex subunit 5

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human JAB1 recombinant protein (Position: M8-S334). Human JAB1 shares 99.4% amino acid (aa) sequence identity with mouse JAB1.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur COPS5

Antigène: COPS5 (COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5))

Autre désignation: COPS5 (COPS5 Produits)

Synonymes: anticorps BcDNA.LD14392, anticorps BcDNA:LD14392, anticorps CG14884, anticorps CH5, anticorps CSN-5, anticorps Csn5, anticorps DCH5, anticorps Dch5, anticorps Dmel\\CG14884, anticorps JAB1, anticorps JAB1/CSN5, anticorps Jab1, anticorps JadBp, anticorps csn5, anticorps dch5, anticorps jab1/csn5, anticorps l(3)89Cf, anticorps l(3)L4032, anticorps l(3)M203, anticorps quo, anticorps COPS5, anticorps MGC76063, anticorps AI303502, anticorps CSN5, anticorps Mov34, anticorps Sgn5, anticorps zgc:73130, anticorps MOV-34, anticorps SGN5, anticorps COP9 signalosome subunit 5, anticorps COP9 signalosome complex subunit 5, anticorps COP9 signalosome subunit 5 S homeolog, anticorps CSN5, anticorps COPS5, anticorps cops5, anticorps CpipJ_CPIJ012314, anticorps Bm1_46585, anticorps VDBG_06932, anticorps LOAG_01443, anticorps csn5, anticorps Cops5, anticorps cops5.S, anticorps csn-5

Sujet: COP9 constitutive photomorphogenic homolog subunit 5 (Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1.

Synonyms: 38 kDa Mov34 homolog antibody|COP9 (constitutive photomorphogenic) homolog subunit 5 antibody|COP9 constitutive photomorphogenic homolog subunit 5 antibody|COP9 signalosome complex subunit 5 antibody|COP9 signalosome subunit 5 antibody|Cop9 subunit 5 antibody|COPS 5 antibody|COPS5 antibody|CSN 5 antibody|CSN5 antibody|JAB 1 antibody|Jun activation domain binding protein 1 antibody|Jun activation domain binding protein antibody|Jun activation domain-binding protein 1 antibody|Jun activation domain-binding protein antibody|MGC3149 antibody|MOV 34 antibody|MOV34 antibody|MOV34 family, 38-KD member antibody|SGN 5 antibody|SGN5 antibody|Signalosome subunit 5 antibody

ID gène: 10987

UniProt: Q92905

Pathways: Cycle Cellulaire