M-CSF/CSF1 anticorps (AA 33-262)

N° du produit ABIN3042763

Cet anticorps Lapin Polyclonal détecte spécifiquement M-CSF/CSF1 dans ELISA et IHC. Il présente une réactivité avec des échantillons de Souris et Rat.Il a été cité dans 1 publication.

Aperçu rapide pour M-CSF/CSF1 anticorps (AA 33-262) (ABIN3042763)

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp M-CSF/CSF1 est non-conjugé

Application: ELISA, Immunohistochemistry (IHC)

Détail du produit anti-M-CSF/CSF1 anticorps

Épitope: AA 33-262

Fonction: Anti-MCSF/CSF1 Antibody

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Homologie: coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 %,88.6% amino acid (aa) sequence identity with human,rat MCSF,respectively.

Attributs du produit: Anti-MCSF/CSF1 Antibody. Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

Purification: Immunogen affinity purified.

Immunogène: E. coli-derived mouse MCSF recombinant protein (Position: K33-E262). Mouse MCSF shares 80.9 % and 88.6% amino acid (aa) sequence identity with human and rat MCSF, respectively.

Isotype: IgG

Information d'application

Indications d'application: ELISA, 0.1-0.5 μg/mL, -Immunohistochemistry (Paraffin-embedded Section), 0.5-1 μg/mL, Mouse, Rat

Commentaires:

Antibody can be supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-M-CSF/CSF1 (ABIN3042763)

Pei, Sun, Zhang, Wang, Ren: "Interstitial tumor-associated macrophages combined with tumor-derived colony-stimulating factor-1 and interleukin-6, a novel prognostic biomarker in non-small cell lung cancer." dans: The Journal of thoracic and cardiovascular surgery, Vol. 148, Issue 4, pp. 1208-1216.e2, (2015) (PubMed).

Détails sur M-CSF/CSF1

Antigène: M-CSF/CSF1 (CSF1) (Colony Stimulating Factor 1 (Macrophage) (CSF1))

Autre désignation: Csf1

Sujet:

Background: M-CSF (or CSF-1) is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival ofmonocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor (CSF1R or M-CSF-R encoded by the c-fms proto-oncogene), M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.

Gene Full Name: colony stimulating factor 1 (macrophage)

Sequence Similarities: Contains 5 cadherin domains.

Poids moléculaire: 130 kDa

ID gène: 12977

UniProt: P07141

Pathways: Signalisation RTK