CYLD anticorps (AA 618-956)

N° du produit ABIN3042782

L’anticorps anti-CYLD Polyclonal Lapin est utilisé pour la détection de CYLD dans des échantillons de Humain et Rat. Il a été validé pour WB.

Aperçu rapide pour CYLD anticorps (AA 618-956) (ABIN3042782)

Antigène: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Reactivité: Humain, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CYLD est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-CYLD anticorps

Épitope: AA 618-956

Fonction: Anti-CYLD Antibody

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-CYLD Antibody (ABIN3042782). Tested in WB applications. This antibody reacts with Human, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human CYLD recombinant protein (Position: D618-K956). Human CYLD shares 97.6% and 97.9% amino acid (aa) sequence identity with mouse and rat CYLD, respectively.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human, Rat

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Détails sur CYLD

Antigène: CYLD (Cylindromatosis (Turban Tumor Syndrome) (CYLD))

Autre désignation: CYLD

Sujet:

Synonyms: Ubiquitin carboxyl-terminal hydrolase CYLD,3.4.19.12,Deubiquitinating enzyme CYLD,Ubiquitin thioesterase CYLD,Ubiquitin-specific-processing protease CYLD,CYLD,CYLD1, KIAA0849,HSPC057,

Tissue Specificity: Detected in fetal brain, testis, and skeletal muscle, and at a lower level in adult brain, leukocytes, liver, heart, kidney, spleen, ovary and lung. Isoform 2 is found in all tissues except kidney. .

Background: CYLD is localized on the long arm of chromosome 16. This gene encodes a cytoplasmic protein with three cytoskeletal-associated protein-glycine-conserved (CAP-GLY) domains that functions as a deubiquitinating enzyme. Mutations in this gene have been associated with cylindromatosis, multiple familial trichoepithelioma, and Brooke-Spiegler syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Sequence Similarities: Belongs to the peptidase C19 family.

Poids moléculaire: 107 kDa

ID gène: 1540

Pathways: Apoptose, Activation of Innate immune Response