DRD5 anticorps (C-Term)

N° du produit ABIN3042836

L’anticorps anti-DRD5 Polyclonal Lapin est utilisé pour la détection de DRD5 dans des échantillons de Souris et Rat. Il a été validé pour WB.

Aperçu rapide pour DRD5 anticorps (C-Term) (ABIN3042836)

Antigène: DRD5 (Dopamine Receptor D5 (DRD5))

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DRD5 est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-DRD5 anticorps

Épitope: AA 388-407, C-Term

Fonction: Anti-Dopamine Receptor D5/DRD5 Antibody

Séquence: LISYNQDTVF HREIAAAYVH

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-Dopamine Receptor D5/DRD5 Antibody (ABIN3042836). Tested in WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of mouse Dopamine Receptor D5, different from the related rat sequence by two amino acids, and from the related human sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Mouse, Rat

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur DRD5

Antigène: DRD5 (Dopamine Receptor D5 (DRD5))

Autre désignation: DRD5

Sujet:

Synonyms: D (1B) dopamine receptor,D (5) dopamine receptor,Dopamine D5 receptor,Drd5,

Tissue Specificity: Brain, liver, placenta, lymphocytes and erythrocytes.

Background: D (1B) dopamine receptor (DRD5), also called DRD1B or DRD1L2 is a protein that in humans is encoded by the DRD5 gene. This gene is mapped to 4p16.1. This gene encodes the D5 subtype of the dopamine receptor. The D5 subtype is a G-protein coupled receptor which stimulates adenylyl cyclase. This receptor is expressed in neurons in the limbic regions of the brain. It has a 10-fold higher affinity for dopamine than the D1 subtype. Pseudogenes related to this gene reside on chromosomes 1 and 2. Compared with DRD1, DRD5 displayed a higher affinity for dopamine and was able to stimulate a biphasic rather than a monophasic intracellular accumulation of cAMP.

Sequence Similarities: Belongs to the class I-like SAM-binding methyltransferase superfamily. Cation-dependent O- methyltransferase family.

Poids moléculaire: 53 kDa

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones, cAMP Metabolic Process, Regulation of long-term Neuronal Synaptic Plasticity