ASIC3 anticorps (N-Term)

N° du produit ABIN3042990

Détail du produit anti-ASIC3 anticorps

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Épitope: AA 56-73, N-Term

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ASIC3 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Acid-sensing ion channel 3(ASIC3) detection. Tested with WB in Human,Mouse,Rat.

Séquence: FLYQVAERVR YYREFHHQ

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Acid-sensing ion channel 3(ASIC3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: acid-sensing(proton-gated) ion channel 3
Protein Name: Acid-sensing ion channel 3

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human ASIC3(56-73aa FLYQVAERVRYYREFHHQ), different from the related rat and mouse sequences by two amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-ASIC3 (ABIN3042990)

Schuhmacher, Callejo, Srivats, Smith: "Naked mole-rat acid-sensing ion channel 3 forms nonfunctional homomers, but functional heteromers." dans: The Journal of biological chemistry, Vol. 293, Issue 5, pp. 1756-1766, (2018) (PubMed).

Détails sur ASIC3

Antigène: ASIC3 (ACCN3) (Amiloride-Sensitive Cation Channel 3 (ACCN3))

Autre désignation: ASIC3 (ACCN3 Produits)

Synonymes: anticorps ACCN3, anticorps Accn3, anticorps DRASIC, anticorps SLNAC1, anticorps TNaC1, anticorps AW742291, anticorps TNAC1, anticorps amiloride-sensitive cation channel 3, anticorps acid sensing ion channel subunit 3, anticorps acid-sensing (proton-gated) ion channel 3, anticorps ACCN3, anticorps ASIC3, anticorps Asic3

Sujet: ASIC3(Acid-Sensing Ion Channel3), also known as TESTIS SODIUM CHANNEL 1(TNAC1) or DORSAL ROOT ACID-SENSING ION CHANNEL(DRASIC), is a protein that in humans is encoded by the ASIC3 gene. ASIC3 belongs to a family of acid-sensing channel proteins that are structurally related to epithelial sodium channel proteins and support acid-activated membrane currents. By radiation hybrid analysis, de Weille et al.(1998) mapped the ACCN3 gene to chromosome 7q35. De Weille et al.(1998) found that human ASIC3 supported an H(+)-gated cation current in COS cells with kinetics similar to those of rat Asic3. Babinski et al.(1999) expressed homomeric human ASIC3 channels in Xenopus oocytes and found that rapid reduction in extracellular pH resulted in a biphasic response characterized by a fast and rapidly desensitizing current followed by a slow and sustained current that returned to baseline only on return to physiologic pH .

Synonyms: ACCN 3 antibody|ACCN3 antibody|ACCN3_HUMAN antibody|Acid sensing ion channel 3 antibody|Acid-sensing ion channel 3 antibody|Amiloride sensitive cation channel 3 antibody|Amiloride sensitive cation channel 3 testis antibody|Amiloride-sensitive cation channel 3 antibody|ASIC 3 antibody|ASIC3 antibody|DRASIC antibody|hASIC 3 antibody|hASIC3 antibody|hTNaC 1 antibody|hTNaC1 antibody|Modulatory subunit of ASIC 2a antibody|Modulatory subunit of ASIC2a antibody|Neuronal amiloride sensitive cation channel 3 antibody|Neuronal amiloride-sensitive cation channel 3 antibody|Proton gated cation channel subunit antibody|SLNAC 1 antibody|SLNAC1 antibody|Testis sodium channel 1 antibody|TNaC 1 antibody|TNaC1 antibody