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Kallikrein 2 anticorps (C-Term)

Cet anticorps anti-Kallikrein 2 est un anticorps Lapin Polyclonal détectant Kallikrein 2 dans WB et IHC. Adapté pour Humain.
N° du produit ABIN3043140

Aperçu rapide pour Kallikrein 2 anticorps (C-Term) (ABIN3043140)

Antigène

Voir toutes Kallikrein 2 (KLK2) Anticorps
Kallikrein 2 (KLK2)

Reactivité

  • 48
  • 6
  • 4
  • 3
  • 1
Humain

Hôte

  • 43
  • 8
  • 1
  • 1
Lapin

Clonalité

  • 45
  • 8
Polyclonal

Conjugué

  • 28
  • 6
  • 4
  • 4
  • 2
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Cet anticorp Kallikrein 2 est non-conjugé

Application

  • 26
  • 25
  • 17
  • 8
  • 7
  • 7
  • 5
  • 4
  • 3
  • 2
  • 1
  • 1
  • 1
Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 15
    • 9
    • 5
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 243-261, C-Term

    Fonction

    Anti-Kallikrein 2/KLK2 Antibody Picoband®

    Séquence

    YTKVVHYRKW IKDTIAANP

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-Kallikrein 2/KLK2 Antibody (ABIN3043140). Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

    Purification

    Immunogen affinity purified.

    Immunogène

    A synthetic peptide corresponding to a sequence at the C-terminus of human Kallikrein 2.

    Isotype

    IgG
  • Indications d'application

    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Human
    Western blot, 0.1-0.5 μg/mL, Human
    1. Gan, L., Lee, I., Smith, R., Argonza-Barrett, R., Lei, H., McCuaig, J., Moss, P., Paeper, B., Wang, K. Sequencing and expression analysis of the serine protease gene cluster located in chromosome 19q13 region. Gene 257: 119-130, 2000. 2. Mason, A. J., Evans, B. A., Cox, D. R., Shine, J., Richards, R. I. Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides. Nature 303: 300-307, 1983. 3. Riegman PH, Vlietstra RJ, Klaassen P, van der Korput JA, Geurts van Kessel A, Romijn JC, Trapman J (May 1989). "The prostate-specific antigen gene and the human glandular kallikrein-1 gene are tandemly located on chromosome 19".

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

    Agent conservateur

    Thimerosal (Merthiolate), Sodium azide

    Précaution d'utilisation

    This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

    Date de péremption

    12 months
  • Antigène

    Kallikrein 2 (KLK2)

    Autre désignation

    KLK2

    Sujet

    Synonyms: Kallikrein-2,3.4.21.35,Glandular kallikrein-1,hGK-1,Tissue kallikrein-2,KLK2,

    Tissue Specificity: Isoform 2 is expressed in pancreas, salivary glands, kidney, colon, prostate gland, testis, spleen and the colon adenocarcinoma cell line T84. .

    Background: KLK2 (KALLIKREIN 2), also called GLANDULAR or PROSTATIC, is a protein that in humans is encoded by the KLK2 gene, and is particularly associated with prostatic tissue. The KLK2 is a member of glandular kallikrein gene family that comprises 25 to 30 highly homologous genes that encode specific proteases involved in the processing of biologically active peptides. The KLK2 gene is mapped to 19q13.33. And the KLK2 gene contains 5 exons. An alternative KLK2 transcript, which they call KLK2-linked molecule (KLM), that arises from the use of an alternate donor site within intron 1. KLM shares only the N-terminal 15-amino acid signal peptide with the original KLK2 protein, the mature proteins display no similarity.

    Sequence Similarities: Belongs to the peptidase S1 family. Kallikrein subfamily.

    Poids moléculaire

    29 kDa

    UniProt

    P20151

    Pathways

    Système du Complément
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