IL2RG anticorps (Middle Region)

N° du produit ABIN3043145

L’anticorps anti-IL2RG Polyclonal Lapin est utilisé pour la détection de IL2RG dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour IL2RG anticorps (Middle Region) (ABIN3043145)

Antigène: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL2RG est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL2RG anticorps

Épitope: Middle Region

Fonction: Anti-IL2 Receptor gamma/IL2RG Antibody

Séquence: HYWYKNSDND KVQKC

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-IL2 Receptor gamma/IL2RG Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of human IL2 Receptor gamma.

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Détails sur IL2RG

Antigène: IL2RG (Interleukin 2 Receptor, gamma (IL2RG))

Autre désignation: IL2RG

Sujet:

Background: IL2RG (INTERLEUKIN 2 RECEPTOR, GAMMA),also known as Common gamma chain or CD132, is a cytokine receptor sub-unit that is common to the receptor complexes for at least six different interleukin receptors:IL-2, IL-4, IL-7, IL-9, IL-15 and interleukin-21 receptor. IL2RG is a member of the type I cytokine receptor family expressed on most lymphocyte (white blood cell) populations, and its gene is found on the X-chromosome of mammals. By fluorescence in situ hybridization and PCR amplification of somatic cell hybrid DNAs, The IL2RG gene is mapped to Xq13.1. The IL2RG gene contains 8 exons and spans approximately 4.2 kb. And the gamma chain is an indispensable component of the functional IL2 receptor. Lymphocytes expressing the common gamma chain can form functional receptors for these cytokine proteins, which transmit signals from one cell to another and programs of cellular differentiation. The sharing of the gamma subunit by several receptors explains why humans and mice that lack IL2 entirely show milder symptoms than those with IL2RG deficiency.

Gene Full Name: interleukin 2 receptor subunit gamma

Sequence Similarities: Belongs to the type I cytokine receptor family. Type 5 subfamily.

Poids moléculaire: 75 kDa

ID gène: 3561

UniProt: P31785

Pathways: Signalistation JAK/STAT, Growth Factor Binding