IL-13 anticorps (Middle Region)

N° du produit ABIN3043198

Détail du produit anti-IL-13 anticorps

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Épitope: AA 80-102, Middle Region

Reactivité: Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL-13 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB in Rat.

Séquence: CNAIHRTQRI LNGLCNQKAS DVA

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Interleukin-13(IL13) detection. Tested with WB in Rat.
Gene Name: interleukin 13
Protein Name: Interleukin-13(IL-13)

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence in the middle region of rat IL-13(80-102aa CNAIHRTQRILNGLCNQKASDVA).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Références pour anticorps anti-IL-13 (ABIN3043198)

Liu, Wang, Cao, Liu, Zou, Li, Yang, Jiao: "Number 2 Feibi Recipe Reduces PM2.5-Induced Lung Injury in Rats." dans: Evidence-based complementary and alternative medicine : eCAM, Vol. 2018, pp. 3674145, (2018) (PubMed).

Zhu, Li, Wu, Lu, You, Li, Li, Yang, Duan: "Acute exposure of ozone induced pulmonary injury and the protective role of vitamin E through the Nrf2 pathway in Balb/c mice." dans: Toxicology research, Vol. 5, Issue 1, pp. 268-277, (2018) (PubMed).

Li, Zhang, Qin, Bi, Liu, Li, Cai, Ma, Chan, Xie, Guan: "CD68 and interleukin 13, prospective immune markers for esophageal squamous cell carcinoma prognosis prediction." dans: Oncotarget, Vol. 7, Issue 13, pp. 15525-38, (2017) (PubMed).

Wang, Liang, Wang, Zhu, Gong, Zhang, Li, Xia: "Th17 down-regulation is involved in reduced progression of schistosomiasis fibrosis in ICOSL KO mice." dans: PLoS neglected tropical diseases, Vol. 9, Issue 1, pp. e0003434, (2016) (PubMed).

Long, Chen, Zhao, Rafaels, Mathias, Liang, Potee, Campbell, Zhang, Gao, Georas, Vercelli, Beaty, Ruczinski, Mathias, Barnes, Chen: "An IL-13 promoter polymorphism associated with liver fibrosis in patients with Schistosoma japonicum." dans: PLoS ONE, Vol. 10, Issue 8, pp. e0135360, (2016) (PubMed).

Li, Li, Zuo, Ke, Yan, Wen, Zhang, Yang: "T-helper type-2 contact hypersensitivity of Balb/c mice aggravated by dibutyl phthalate via long-term dermal exposure." dans: PLoS ONE, Vol. 9, Issue 2, pp. e87887, (2014) (PubMed).

Détails sur IL-13

Antigène: IL-13 (IL13) (Interleukin 13 (IL13))

Autre désignation: IL13 (IL13 Produits)

Synonymes: anticorps IL13, anticorps IL-13, anticorps P600, anticorps Il-13, anticorps L13, anticorps interleukin 13, anticorps IL13, anticorps Il13

Sujet: IL-13, Interleukin 13, is a protein that in humans is encoded by the IL-13 gene. IL-13 is cytokine secreted by many cell types, but especially T helper type 2(Th2) cells that is an important mediator of allergic inflammation and disease. The IL-13 gene is mapped to 5q23-q31. IL-13 induces its effects through a multi-subunit receptor that includes the alpha chain of the IL-4 receptor(IL-4Ralpha) and at least one of two known IL-13-specific binding chains. IL-13 acts more prominently as a molecular bridge linking allergic inflammatory cells to the non-immune cells in contact with them, thereby altering physiological function.

Synonyms: Allergic rhinitis antibody|ALRH antibody|BHR1 antibody|Bronchial hyperresponsiveness 1(bronchial asthma) antibody|IL 13 antibody|IL-13 antibody|Il13 antibody|IL13_HUMAN antibody|Interleukin 13 antibody|Interleukin-13 antibody|MGC116786 antibody|MGC116788 antibody|MGC116789 antibody|NC30 antibody|P600 antibody

UniProt: P42203

Pathways: Signalistation JAK/STAT, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport