IL12B anticorps (N-Term)

N° du produit ABIN3043199

Il existe 1 publication pour ce produit. L’anticorps anti-IL12B Polyclonal Lapin est utilisé pour la détection de IL12B dans des échantillons de Humain. Il a été validé pour WB.

Aperçu rapide pour IL12B anticorps (N-Term) (ABIN3043199)

Antigène: IL12B (Interleukin 12 beta (IL12B))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IL12B est non-conjugé

Application: Western Blotting (WB)

Détail du produit anti-IL12B anticorps

Épitope: N-Term

Fonction: Anti-IL12 p40/IL12B Antibody

Séquence: IWELKKDVYV VELDWYPD

Specificité: No cross reactivity with other proteins.

Réactivité croisée (Details): No cross-reactivity with other proteins

Attributs du produit: Anti-IL12 p40/IL12B Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminus of human IL-12(p40).

Isotype: IgG

Information d'application

Indications d'application: Western blot, 0.1-0.5 μg/mL, Human

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Thimerosal (Merthiolate) and Sodium azide: POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C,-20 °C

Stockage commentaire: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Date de péremption: 12 months

Références pour anticorps anti-IL12B (ABIN3043199)

Dong, Xia, Chen, Chen, Zhang: "Anti-arthritis activity of cationic materials." dans: Journal of cellular and molecular medicine, Vol. 14, Issue 7, pp. 2015-24, (2011) (PubMed).

Détails sur IL12B

Antigène: IL12B (Interleukin 12 beta (IL12B))

Autre désignation: IL12B

Sujet:

Background: IL-12, Interleukin 12, heterodimerizes with the IL12 p35 subunit to form IL12 and with the IL23 p19 subunit to form IL23. IL12b p 40 exists as a monomer and as a homodimer. This gene encodes a subunit of Interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. The IL-12b gene contains 8 exons, the first and last of which are noncoding. By PCR analysis of DNA from rodent/human cell hybrids containing intact chromosomes or translocation chromosomes, the IL-12b gene is mapped to 5q31-q33.This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen.

Gene Full Name: interleukin 12B

Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.

Poids moléculaire: 20 kDa

ID gène: 3593

UniProt: P29460

Pathways: Signalistation JAK/STAT, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Activated T Cell Proliferation