KIAA1524 anticorps (C-Term)

N° du produit ABIN3043277

Détail du produit anti-KIAA1524 anticorps

Antigène: KIAA1524

Épitope: AA 854-889, C-Term

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KIAA1524 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Protein CIP2A(KIAA1524) detection. Tested with WB in Human,Mouse.

Séquence: EVQKAQLEGR LEEKESLVKL QQEELNKHSH MIAMIH

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Protein CIP2A(KIAA1524) detection. Tested with WB in Human,Mouse.
Gene Name: KIAA1524
Protein Name: Protein CIP2A

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human KIAA1524 (854-889aa EVQKAQLEGRLEEKESLVKLQQEELNKHSHMIAMIH), different from the related mouse sequence by three amino acids.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur KIAA1524

Antigène: KIAA1524

Autre désignation: KIAA1524 (KIAA1524 Produits)

Synonymes: anticorps CIP2A, anticorps p90, anticorps AA408511, anticorps AU018569, anticorps Cip2a, anticorps Kiaa1524, anticorps KIAA1524, anticorps LOC100222895, anticorps RGD1310335, anticorps cell proliferation regulating inhibitor of protein phosphatase 2A, anticorps RIKEN cDNA C330027C09 gene, anticorps KIAA1524, anticorps cell proliferation regulating inhibitor of protein phosphatase 2A L homeolog, anticorps CONSTANS interacting protein 2a, anticorps CIP2A, anticorps C330027C09Rik, anticorps KIAA1524, anticorps cip2a.L, anticorps CIP2a, anticorps cip2a, anticorps Cip2a

Sujet: Protein CIP2A, also known as cancerous inhibitor of PP2A (CIP2A), is a protein that in humans is encoded by the KIAA1524 gene. CIP2A is required for the malignant cellular growth and for in vivo tumor formation. In accordance with the oncogenic role of CIP2A, overexpression of CIP2A promotes Ras-elicited cell growth and transforms immortalized human cells (HEK-TERVs). More recently CIP2A has been shown to regulate phosphorylation and activity of many other oncoproteins and to drive malignant cell growth and tumorigenesis in various human cancer types. Importantly, CIP2A deficient mice are viable, suggesting that targeting of oncogenic function of CIP2A would not result in serious side-effects.

Synonyms: Cancerous inhibitor of PP2A antibody|Cancerous Inhibitor of Protein Phosphatase 2A antibody|CIP2A antibody|CIP2A_HUMAN antibody| FLJ12850 antibody|Kiaa1524 antibody|MGC163436 antibody|p90 antibody|p90 autoantigen antibody|Protein CIP2A antibody

ID gène: 57650