PLK1 anticorps (AA 86-430)
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- Antigène Voir toutes PLK1 Anticorps
- PLK1 (Polo-Like Kinase 1 (PLK1))
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Épitope
- AA 86-430
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Reactivité
- Humain, Souris, Rat
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Hôte
- Lapin
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Clonalité
- Polyclonal
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Conjugué
- Cet anticorp PLK1 est non-conjugé
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Fonction
- Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PLK1(PLK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Réactivité croisée (Details)
- No cross reactivity with other proteins.
- Attributs du produit
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Rabbit IgG polyclonal antibody for Serine/threonine-protein kinase PLK1(PLK1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: polo-like kinase 1
Protein Name: Serine/threonine-protein kinase PLK1 - Purification
- Immunogen affinity purified.
- Immunogène
- E.coli-derived human PLK1 recombinant protein (Position: K86-N430). Human PLK1 shares 95.4% and 96.2% amino acid (aa) sequence identity with mouse and rat PLK1, respectively.
- Isotype
- IgG
- Top Product
- Discover our top product PLK1 Anticorps primaire
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- Indications d'application
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Concentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Conseil sur la manipulation
- Avoid repeated freezing and thawing.
- Stock
- 4 °C/-20 °C
- Stockage commentaire
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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- Antigène
- PLK1 (Polo-Like Kinase 1 (PLK1))
- Autre désignation
- PLK1 (PLK1 Produits)
- Synonymes
- anticorps PLK, anticorps STPK13, anticorps plk, anticorps PLK-1, anticorps Plx1, anticorps stpk13, anticorps Plk, anticorps cb525, anticorps cb636, anticorps ik:tdsubc_2d1, anticorps wu:fb37g11, anticorps wu:fb76g03, anticorps xx:tdsubc_2d1, anticorps polo like kinase 1, anticorps polo like kinase 1 S homeolog, anticorps polo-like kinase 1, anticorps polo-like kinase 1 (Drosophila), anticorps Serine/threonine-protein kinase plk-1, anticorps PLK1, anticorps plk1.S, anticorps plk1, anticorps Plk1, anticorps plk-1
- Sujet
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Serine/threonine-protein kinase PLK1, also known as polo-like kinase 1 (PLK-1) or serine/threonine-protein kinase 13(STPK13), is an enzyme that in humans is encoded by the PLK1 (polo-like kinase 1) gene. Plk1 is an early trigger for G2/M transition. It supports the functional maturation of the centrosome in late G2/early prophaseand establishment of the bipolar spindle. Also, Plk1 phosphorylates and activates cdc25C, a phosphatase that dephosphorylates and activates the cyclinB/cdc2 complex. Studies have shown that the loss of PLK1 expression can inducepro-apoptotic pathways and inhibit growth. Based on yeast and murine studies of meiosis, human PLK1 may also have a regulatory function in meiosis.
Synonyms: Cell cycle regulated protein kinase antibody|PLK 1 antibody|PLK antibody|PLK-1 antibody| plk1 antibody|PLK1_HUMAN antibody|Polo like kinase 1 antibody|Polo-like kinase 1 antibody| Serine/threonine protein kinase 13 antibody|Serine/threonine protein kinase PLK1 antibody| Serine/threonine-protein kinase 13 antibody|Serine/threonine-protein kinase PLK1 antibody| STPK 13 antibody|STPK13 antibody - ID gène
- 5347
- UniProt
- P53350
- Pathways
- Cycle Cellulaire, M Phase
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