OMG anticorps (N-Term)
Aperçu rapide pour OMG anticorps (N-Term) (ABIN3043375)
Antigène
Voir toutes OMG AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 64-99, N-Term
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Fonction
- Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody
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Séquence
- YNHFTDLHNQ LTQYTNLRTL DISNNRLESL PAHLPR
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Réactivité croisée (Details)
- No cross-reactivity with other proteins.
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Attributs du produit
- Anti-Oligodendrocyte myelin glycoprotein/OMG Antibody (ABIN3043375). Tested in WB applications. This antibody reacts with Human, Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.
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Purification
- Immunogen affinity purified.
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Immunogène
- A synthetic peptide corresponding to a sequence at the N-terminus of human OMG, different from the related mouse sequence by two amino acids.
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Isotype
- IgG
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Indications d'application
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Western blot, 0.1-0.5 μg/mL, Human, Mouse, Rat
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Commentaires
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
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Concentration
- 500 μg/mL
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Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Conseil sur la manipulation
- Avoid repeated freezing and thawing.
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Stock
- 4 °C,-20 °C
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Stockage commentaire
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Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
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- OMG (Oligodendrocyte Myelin Glycoprotein (OMG))
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Autre désignation
- OMG
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Sujet
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Synonyms: Oligodendrocyte-myelin glycoprotein,OMG,OMGP,
Tissue Specificity: Oligodendrocytes and myelin of the central nervous system.
Background: Oligodendrocyte-myelin glycoprotein is a protein that in humans is encoded by the OMG gene. This gene is mapped to 17q11-q12. OMG, like neurofibromin (NF1), has growth suppressive effects and downregulates mitogenic signaling pathways closely related to those influenced by neurofibromin. Overexpression of OMG alters mitogenic signaling in fibroblasts. Cells overexpressing OMG grow more slowly in serum compared to controls and show a partial G1 block upon cell cycle analysis.
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Poids moléculaire
- 50 kDa
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ID gène
- 4974
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UniProt
- P23515
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Pathways
- Neurotrophin Signaling Pathway, Regulation of Cell Size
Antigène
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