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Galectin 3 anticorps (AA 153-264)

L’anticorps Lapin Polyclonal anti-Galectin 3 a été validé pour WB et IHC. Il convient pour détecter Galectin 3 dans des échantillons de Souris et Rat.
N° du produit ABIN3043400

Aperçu rapide pour Galectin 3 anticorps (AA 153-264) (ABIN3043400)

Antigène

Voir toutes Galectin 3 (LGALS3) Anticorps
Galectin 3 (LGALS3)

Reactivité

  • 220
  • 123
  • 74
  • 6
  • 2
  • 2
  • 2
  • 1
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Souris, Rat

Hôte

  • 195
  • 55
  • 17
  • 3
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Lapin

Clonalité

  • 155
  • 119
Polyclonal

Conjugué

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  • 1
Cet anticorp Galectin 3 est non-conjugé

Application

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Western Blotting (WB), Immunohistochemistry (IHC)
  • Épitope

    • 23
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    AA 153-264

    Fonction

    Anti-Galectin 3/LGALS3 Antibody

    Réactivité croisée (Details)

    No cross-reactivity with other proteins

    Attributs du produit

    Anti-Galectin 3/LGALS3 Antibody (ABIN3043400). Tested in IHC, WB applications. This antibody reacts with Mouse, Rat. This is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications.

    Purification

    Immunogen affinity purified.

    Immunogène

    E.coli-derived mouse Galectin 3 recombinant protein (Position: K153-I264). Mouse Galectin 3 shares 88% and 91% amino acid (aa) sequence identity with human and rat Galectin 3, respectively.

    Isotype

    IgG
  • Indications d'application

    Western blot, 0.1-0.5 μg/mL, Mouse, Rat
    Immunohistochemistry (Paraffin-embedded Section), 2-5 μg/mL, Mouse, Rat

    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions

    For Research Use only
  • Format

    Lyophilized

    Reconstitution

    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

    Concentration

    500 μg/mL

    Buffer

    Each vial contains 4 mg Trehalose, 0.9 mg NaCl and 0.2 mg Na2HPO4.

    Conseil sur la manipulation

    Avoid repeated freezing and thawing.

    Stock

    4 °C,-20 °C

    Stockage commentaire

    Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
  • Antigène

    Galectin 3 (LGALS3)

    Autre désignation

    LGALS3

    Sujet

    Synonyms: Galectin-3;Gal-3;35 kDa lectin;Carbohydrate-binding protein 35;CBP 35;Galactose-specific lectin 3;IgE-binding protein;L-34 galactoside-binding lectin;Laminin-binding protein;Lectin L-29;Mac-2 antigen;Lgals3;

    Tissue Specificity: The highest levels are found in activated macrophages.

    Background: Galectin-3 (GAL3), also known as LGALS3, MAC2 or GALBP, is a member of the lectin family, of which 14 mammalian galectins have been identified. Galectin-3 is encoded by a single gene, it located on chromosome 14, locus q21–q22. It is expressed in the nucleus, cytoplasm,mitochondrion, cell surface, and extracellular space. Studies have also shown that the expression of galectin-3 is implicated in a variety of processes associated with heart failure, including myofibroblast proliferation, fibrogenesis, tissue repair, inflammation, and Ventricular remodeling. Galectin-3 is expressed in various tissues and organs, but is significantly absent in normal hepatocytes.

    Sequence Similarities: Contains 3 cystatin kininogen-type domains.

    Poids moléculaire

    29 kDa

    ID gène

    16854

    UniProt

    P16110

    Pathways

    Signalisation RTK
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